Stem Cell Therapy for Musculoskeletal Disorders: A Revolutionary Treatment
Nearly 2 billion people around the world are affected with musculoskeletal disorders. One-third of the UK’s population suffers from musculoskeletal conditions such as back pain or arthritis.
Similarly, nearly 130 million US adults have musculoskeletal conditions.
Musculoskeletal defects are one of the leading causes of worldwide disabilities.
Musculoskeletal disorders impact the mobility and strength of a person.
These diseases and injuries severely impact the quality of life. It could lead to mental stress, early retirement from work, depression, anxiety, and limited participation in social activities.
There are more than 150 types of diseases that can affect the muscles, bones, joints, tendons, or connective tissues leading to musculoskeletal disorders.
Stem cell therapy using mesenchymal stem cells has highlighted promising results for treating musculoskeletal pain.
MSCs indicate chondrogenesis properties that help to regenerate damaged cartilage for skeletal development.
In this blog, we will explore the benefits of stem cells for orthopedic injuries.
Insights into Musculoskeletal Disorders
The musculoskeletal system comprises muscles, bones, and joints. It helps to regulate the movements of the body. Injuries and diseases limit the functions of the joints and muscles. This can lead to lifelong paralysis or limited mobility. For example, a person with a hip or knee injury cannot participate in heavy lifting duties.
Various musculoskeletal diseases that affect different parts of the body include –
- Joints – These are the locations within the body where two bones meet. Diseases such as spondylitis, rheumatoid arthritis, and osteoarthritis cause degeneration of the joints.
- Bones – Traumatic fractures due to injuries or diseases such as osteoporosis can make the bones weak and brittle.
- Muscles – An aging-related disease that causes muscle loss.
Common causes of short-term musculoskeletal pain are –
- Bruises to the bone
- Fractures in the bone
- Dislocation of a joint
- Mechanical injuries such as carpal tunnel syndrome or tennis elbow
- Torn muscles or tendons
- Cramps in the muscles
- Bone infection or osteomyelitis
Types of Disorders
Common musculoskeletal disorders include –
- Tendonitis – This is a disease that causes inflammation of the tendons, a connective cord joining muscles to bones. Repetitive actions or sudden injuries cause tendonitis, which impacts the mobility of the joints.
- Bone Fractures – A complete or partial cracking of the bone is called a fracture. Accidents to the wrist, ankle, and hips are common causes of this type of musculoskeletal injury.
- Fibromyalgia – A type of disease that causes soft tissue and muscle pain throughout the body.
- Rheumatoid Arthritis – An autoimmune disease that attacks the healthy tissues of the body and causes joint inflammation.
- Osteoarthritis – A disease that impacts the joints and degenerates the cartilage inside limiting movement in older people.
- Carpal Tunnel Syndrome – The compression of the median nerve in the wrist causes a sensation of extreme pain or numbness in the fingers. Wrist injuries, ganglion cysts, and autoimmune disorders increase the risk of this type of condition.
- Systemic Lupus Erythematosus – Joint pain and swelling due to the immune system attacking the healthy tissues of the body.
- Scleroderma – A type of disease that causes too much collagen production and makes the skin tissues thick causing inflammation and pain in the joints, bones, and muscles.
- Gout – A type of inflammatory arthritis that induces joint pain and swelling.
Impact on Life
Musculoskeletal defects degrade the quality of life in the following ways –
- It causes pain and loss of movement.
- Increases the risk of cardiovascular diseases.
- Imposes voluntary or early retirement from work.
- Increases economic burden due to healthcare expenses.
Traditional Treatment Options
Traditional treatment and pain management options for musculoskeletal disorders are –
- Acupuncture – This is a type of minimally invasive targeted treatment where needles are inserted at strategic points.
- Chiropractic care – This is a manual therapy where that includes manipulation of the spine.
- Compression therapy – This is a type of alternative treatment where elastic socks or bandages are used to offer extra support to the legs, feet, and ankles. This treatment improves lower body part blood circulation.
- Osteopathic manipulative treatment – A type of therapy that includes gentle pressure application and stretching to improve the alignment and functions of the bones and muscles.
- Massage therapy – A manual method to relieve a patient from joint or bone-related pain through the application of pressure to the joints, muscles, or ligaments.
- Pain medications – Opioids, antidepressants, topical analgesics, and steroidal injections are all examples of over-the-counter drugs for musculoskeletal pain.
- Hydrotherapy – Also known as water therapy, this is an occupational treatment that uses the buoyancy of water to offer pain relief, improve joint functions, and enhance the overall body balance. This treatment can help to heal osteoarthritis, muscle tears, and lower back pain.
- Steroidal injections – Corticosteroid injections can reduce inflammation and pain with short-term relief for osteoarthritis and rheumatoid arthritis patients.
- Surgery – Surgical options for musculoskeletal disorders are called orthopedic surgeries. Different categories of surgeries are –
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- Soft tissue repair – A surgical option to repair torn ligaments and replace the damaged tissues.
- Joint fusion surgery – A surgical procedure to fuse two or more bones.
- Osteotomy – Surgical realignment of joints and bones to fix deformities and reinstate body balance.
- Joint replacement – Replacement of damaged joints with metal, prosthesis, or ceramic.
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Conventional Treatment Challenges
Several challenges for musculoskeletal disorders conventional treatment indicate –
- Lack of personalized treatment plans for specific conditions and symptoms.
- Short-term and ineffective treatment that cannot address the root cause of the disease.
- No pain reduction through opioid medication.
- An increased rate of surgery indicates an increased rate of post-surgical complications.
- There is no fixed recovery or rehabilitation time for patients who went through traditional treatment for musculoskeletal injuries or diseases.
Overview of Stem Cell Therapy
Stem cell therapy is the newest treatment option in the healthcare block that promotes natural healing from injuries and diseases.
Stem cells act as the body’s repair system. It repairs damaged tissues and cells.
Moreover, it is a minimally invasive and non-surgical treatment that not only alleviates pain but also addresses the root cause of a disease.
Types of Stem Cells
Varieties of stem cells include –
- Mesenchymal stem cells – Found in the adipose layer, human umbilical cord tissues (Wharton’s Jelly), and bone marrow, these stem cells are effective in healing orthopedic conditions.
- Embryonic stem cells – A type of adult stem cells that can convert into different types of cells.
- Adult stem cells – Present in the tissues and different organs of an adult, these cells differentiate and transform into several types of organ tissues.
Mechanisms of Stem Cells
Multipotent MSCs have different functions. Some of the properties highlight –
- Tissue repair – The ability of MSCs to heal immune-related diseases and repair skeletal tissue damage to the bone and cartilage.
- Tissue regeneration – MSCs stimulate the regrowth of tissues by accelerating the production of growth factors, mitochondria, and nucleotides.
- Immunomodulation – It prevents the actions of T-cells and tolerogenic dendritic cells to improve immune system responses.
- Paracrine signaling – Mesenchymal stem cells release chemokines and cytokines to promote cell signaling.
- Cell differentiation – Stem cells are able to differentiate between different types of cells, migrate to the injured area, and transform into necessary cells to promote self-healing.
How is Stem Cell Therapy a Game Changer?
The top reasons why stem cell therapy is a novel and therapeutic alternative to traditional treatment for musculoskeletal disorders are –
- Addresses the root cause of the injury or disease and provides long-term relief.
- The ability of stem cells to reconstruct damaged bones and joints to improve mobility and functions.
- Restores the ability of the immune system to support natural tissue regeneration.
- The potential of stem cells in healing several conditions such as ligament tears, tendon injuries, muscle injuries, joint injuries, and arthritic problems.
Application of Stem Cell Therapy in Musculoskeletal Disorders
Stem cell therapy has shown promising results for treating musculoskeletal disorders through bone, cartilage, and tendon regeneration. Moreover, it helps to reverse the effects of joint diseases such as osteoarthritis. Also, it cures degenerative disc diseases of the spine and alleviates musculoskeletal pain that is unaltered even after standard treatment.
Stem Cell Therapy for Joint Injuries
Stem cell treatment results for joint pain show –
- Osteoarthritis – Stem cell therapy can restore joint movement, and reduce pain, and other symptoms of osteoarthritis. Stem cell therapy for cartilage repair releases anti-inflammatory factors.
- Rheumatoid arthritis – MSCs prevent the growth of cytotoxic T-cells strengthening the immune system to fight inflammation repair damaged tissue and reduce pain for RA patients.
- Joint degeneration – The ability of stem cells to make artificial tissues to repair damaged bones, cartilage, and ligaments.
Stem Cell Treatment for Ligaments
Stem cell therapy is an effective treatment for healing ligament and tendon-related injuries. Some of the treatment benefits indicate –
- Tendonitis – Reduces inflammation and pain, promotes chondrogenesis or the formation of chondrocytes (cartilage cells), and replaces damaged cells.
- Anterior Cruciate Ligament (ACL) injuries – A minimally-invasive and non-surgical treatment procedure to reduce inflammation, regulate the immune system, relieve pain, and improve the functions of the knee.
Overview of Stem Cell Therapy for Spinal Conditions
The results of stem cell therapy for chronic back pain and spinal cord injuries showcase –
- Helps to repair damaged neural tissues. MSCs can prevent inflammation of the joints, cartilage, and tissues. Additionally, it can eliminate the chances of cell death. Moreover, stem cells can regenerate lost neurons to repair the spinal cord.
- Mesenchymal stem cells restore the cellularity of degenerative discs. This controls inflammation.
- Stem cells treat the root cause of the pain without medicines and surgery.
Read Also: Mesenchymal Stem Cell Therapy: Promising New Pulmonary Fibrosis Treatment
Clinical Reports of Stem Cell Therapy
Stem cell therapy provides muscle recovery, rejoins meniscal tears, and repairs tendon and ligament injuries.
Case Studies
- Case Study 1(Stem Cell Therapy for Arthritis) – 329 osteoarthritis patients were given mesenchymal stem cell therapy using the intraarticular method. These patients were evaluated 2 years post-treatment. The results of stem cell therapy for knee pain without surgery indicated significant pain relief regardless of age and gender. Most importantly, it helped them avoid knee replacement surgery.
- Case Study 2(Regenerative Therapy for Bone Healing) – Elsei went through a car accident that caused a torn disc injury. She got stem cell therapy to repair her torn disc and manage excruciating pain. She recovered up to 90 percent and did not need any pain medications after the therapy.
Comparative Studies
Differences between traditional treatment and stem cell therapy for musculoskeletal injuries are –
Stem Cell Therapy vs. Conventional Treatments
Differences | Stem Cell Therapy | Traditional Treatment |
Nature of Treatment | A minimally invasive and non-surgical treatment method. | A combination of medicines, non-surgical therapies, and invasive surgeries for extreme cases. |
Effects of Treatment | Long-term improvement of joint mobility, reduced pain, inflammation, swelling, and stiffness. | Short-term term pain relief only. However, there can be significant improvement in a patient’s condition after surgery. |
Results of Treatment | Helps to repair tissues, regenerate cartilage, and promote natural healing to reform lost cells. | Replacement of injured joints and damaged cartilage with artificial materials such as prostheses. |
Costs of Treatment | The cost of the treatment depends on the weight, height, gender, and age of the patient. Moreover, the type of stem cell, the type of administration method, and the number of doses impact the treatment expenses. | The costs of surgical methods are higher than minimally invasive stem cell therapy. |
Benefits of Wharton’s Jelly MSCs for Musculoskeletal Complications
The beneficial results of stem cell therapy indicate –
- Enhances chondrogenesis or the formation of new cartilage.
- Promotes the regeneration of tissues and ligaments.
- Promotes the secretion of paracrine and growth factors to prevent inflammation of the joints and tissues.
- Improves bone-forming osteoblasts.
- MSCs can produce a collagen-proteoglycan matrix that heals bone fractures.
- Reduces cartilage defects, improves joint functions, and reduces pain related to osteoarthritis.
- Patients with knee meniscal tears highlighted improved mobility and sports activities 2 years after stem cell therapy.
- It is a viable alternative to surgeries, physical therapy, chiropractic care, hydrotherapy, and other conventional treatment methods with better results.
- Stem cell therapy for shoulder pain and injuries showcases healing from rotator cuff tears, and shoulder sprains, and stops the progress of diseases such as arthritis.
Stem Cell Therapy Administration Procedure
Stem cells are administered to patients using the following methods –
- Intravenous infusions are injected through ventricular channels.
- Intraarticular injections are given through local joints near the affected region.
- Intramuscular injections are given through appropriate muscles near the injured or disease-affected area.
Stem cell doctors are experts who determine the best administration process based on the severity of the patient’s condition, their age, and other medical influences.
Future Findings of Stem Cell Therapy for Musculoskeletal Disorders
Stem cells are novel regenerative medicine for musculoskeletal injuries. Scope of improving the future of healthcare with stem cells highlight –
- Regenerative solutions – Natural repairing of damaged tissues, ligaments, muscles, and bones.
- Personalized medicine – The application of stem cell therapy depends on the patient’s age, gender, weight, height, and other conditions. It is a personalized approach that includes different stem cell doses for different patients.
- Bioengineering – Stem cells are prevalently being used to develop biomaterials for tissue engineering and gene modification to heal several diseases.
- Platelet-rich plasma (PRP) injections – A combination of PRP injections and stem cell therapy can improve the results of musculoskeletal treatment.
Read Also: Remarkable Results of Stem Cell Therapy for Glenohumeral Osteoarthritis Treatment
Takeaway
Stem cell therapy is a revolutionary treatment because it not only promotes the self-healing of the body but also eliminates the risks and expenses related to costly and painful surgeries.
The ability of MSCs to transform into different types of cells and tissues is a promising sign of regenerative treatment.
The Life Altering Stem Cell Therapy Institute is a renowned clinic in Mazatlán. Explore the benefits of stem cell therapy for back pain & spinal damage with certified experts.
Talk to us today and get the best treatment option to heal your musculoskeletal injury or disease. Experience long-term relief and free movement.
Mesenchymal Stem Cell Therapy: Promising New Pulmonary Fibrosis Treatment
Nearly 20 out of 100,000 people across the world suffer from pulmonary fibrosis.
40,000 US citizens are diagnosed with pulmonary fibrosis every year.
Lung fibrosis causes breathing difficulties and destroys the air sacs within the lungs.
Pulmonary fibrosis affects the respiratory system. This gradually declines lung functions and breathing abilities.
Genes, autoimmune diseases, viral infections, and environmental factors cause this type of disease.
Mesenchymal stem cells (MSCs) for treatment purposes are derived from human umbilical cord tissues (Wharton’s Jelly). This type of stem cell can convert into cartilage, bone, and muscle cells. However, this type of stem cells are also found in the adipose tissue and bone marrow.
MSCs secrete paracrine factors at the injury site. This helps in –
- Endothelial and epithelial permeability regulation
- Reduction of inflammation
- Tissue repair enhancement
- Prevent bacterial infections
- Superoxide dismutase secretion to prevent reactive oxygen damage to the lungs
- Promotes cell communication
This blog will explore the benefits and results of MSC treatment for fibrosis.
Read Also: Stem Cell Therapy for Autoimmune Diseases
Insights Into Pulmonary Fibrosis
Pulmonary fibrosis is lung tissue scarring that impacts the alveoli or the air sacs inside the lungs. Naturally, the lungs lose their elasticity and the tissues become stiff. The alveoli promote oxygenation in the bloodstream. However, fibrosis is a progressive disease that limits the oxygen supply into the blood and causes shortness of breath.
It is important to note that pulmonary fibrosis is different than chronic obstructive pulmonary disease. Over 100,000 US citizens suffer from this disease. Fibrosis of the lungs is more prominent in people over 50 years.
Causes
Pulmonary fibrosis is caused due to –
- Genes – People who suffer from this type of disease develop abnormal genes and have a high chance of passing them down to their predecessors.
- Medical Conditions – Multiple autoimmune conditions such as Sjogren’s syndrome, polymyositis, and scleroderma increase the chances of pulmonary fibrosis.
- Exposure to Toxins – Several environmental toxins such as silica, coal dust, and asbestos increase the risk of developing pulmonary fibrosis.
- Radiation Therapy – High-energy X-rays for cancer treatment can develop pulmonary fibrosis in patients.
Symptoms
Infections in the respiratory tract and the common cold could be symptoms of lung scarring. Signs of pulmonary fibrosis indicate –
- Shortness of breath
- Fatigue and tiredness
- Unexplained weight loss
- Clubbed fingertips
- Bluish skin around the eyes due to lack of oxygen in the blood also known as cyanosis
Diagnosis
Pulmonary fibrosis can be effectively diagnosed with the following tests –
- Blood tests – Blood samples are collected to identify different types of diseases present in the patient’s body.
- Imaging tests – CT scans and chest X-ray confirm the presence of pulmonary fibrosis.
- Biopsy – A surgical method to extract a tiny portion of the lung tissue to examine the presence of pulmonary fibrosis.
- Breathing tests – Spirometry and lung volume tests are some methods to determine the lung’s strength.
- Lung Diffusion test – A particular test to measure the level of oxygen in the patient’s bloodstream.
Effects of Fibrosis on the Lungs
Patients with pulmonary fibrosis have breathing difficulties. Other effects of this disease on the lungs highlight –
- Thickening of the lung tissues around the air sacs or alveoli.
- Lung tissue scarring is known as fibrosis.
- Reduced absorption of oxygen into the bloodstream of the patient.
- Decreased levels of energy and lung capacity lead to shortness of breath.
- Loss of lung elasticity prevents expansion and contraction of the lungs during breathing.
Types of Pulmonary Fibrosis
PF is a type of interstitial lung disease that occurs due to the inflammation of the air sacs in the lungs. There are different types of pulmonary fibrosis caused due to various factors. Some of them are –
- Idiopathic pulmonary fibrosis – A type of pulmonary fibrosis where the cause is undetected.
- Hypersensitivity pneumonitis – Inhaling dust for a long time can develop this disease.
- Asbestosis – Breathing a heavy amount of asbestos can cause lung fibrosis.
- Familial pulmonary fibrosis – A rare type of lung fibrosis caused due to gene transfer from one family member to another.
- Disease-related pulmonary fibrosis – Various diseases such as rheumatoid arthritis can cause lung tissue scarring.
Traditional Treatment Options
Pulmonary fibrosis treatment options are –
- Medications – Several drugs such as pirfenidone, azathioprine, and anti-acid medications are given to pulmonary fibrosis patients.
- Oxygen therapy – Extra oxygen is given to patients in a hospital setting through masks or nose tubes to improve their breathing conditions and lung functions.
- Lung transplant – A surgical method to replace the damaged lungs of a patient. It is mandatory to find a medically cleared donor with a healthy lung for this type of surgery.
Read Also: A New Approach for Lung Disease Treatment with Stem Cell Therapy
Limitations of Conventional Treatment
Limitations for pulmonary fibrosis treatment are –
- Inability to determine the cause behind functional limitations of the lungs.
- Pulmonary fibrosis patients go through other types of lung and heart diseases that decrease their life expectancy.
- A limited number of healthy lung donors.
- Several side effects occur from pulmonary fibrosis medicines.
- Oxygen therapy is ineffective if the patient’s lung condition is very poor.
Breakthrough of Stem Cells as a Regenerative Medicine for Lung Disorders
Stem cell therapy offers excellent improvement for lung conditions such as COVID-19, emphysema, and fibrosis.
Different types of stem cells are multipotent, totipotent, and pluripotent. Stem cells are the natural repair system of the body promoting self-healing. Mesenchymal stem cells, adult stem cells, embryonic stem cells, and induced pluripotent stem cells are prominently used for treatment purposes.
Characteristics of Mesenchymal Stem Cells
MSCs have multiple properties including –
- Regulation of the immune system and prevents bacterial infections.
- Reduction of inflammation through increased production of anti-inflammatory factors and proliferation of T-regulatory cells.
- Stem cells promote tissue repair by accelerating the production of growth factors such as cytokines and chemokines.
- Helps to regenerate the alveoli or air sacs of the lung tissues to improve their functions.
- MSCs can be easily harvested and isolated for diseases.
- Mesenchymal stem cells can self-renew and transform into other types of stem cells.
How does MSC Treatment Work for Fibrosis?
MSCs for idiopathic pulmonary fibrosis (IPF) help patients in the following ways –
- Secretes keratinocyte growth factors to reduce inflammation of the lung tissues.
- Regenerate damaged lung tissues through cytokine and chemokine production.
- MSCs release extracellular vesicles known as exosomes that can inhibit inflammatory actions.
- Helps to form connective tissues that support the lungs and improve their functions.
- MSCs prevent cell apoptosis or death.
- Mesenchymal stem cells secrete superoxide dismutase to protect the lungs against reactive oxygen damage.
Stem Cell Therapy Clinical Research for Pulmonary Fibrosis
Several studies indicate beneficial features of MSCs to reverse the effects of pulmonary fibrosis.
MSCs secrete SOD that reduces the level of collagen production to prevent deposition of intercellular matrix. This significantly improves pulmonary fibrosis.
Advancements of Stem Cell Research in Lung Diseases
Several researches indicate the following results of stem cells for managing lung diseases –
- Stem cells repair lung tissue damage for chronic bronchitis and emphysema patients.
- Stem cell therapy is an ideal alternative for expensive lung transplant surgeries.
- A new method to generate induced pluripotent stem cells from skin biopsy samples of end-stage lung disease patients. These cells are used to create scaffolds for lung implantation.
Stem Cell Therapy vs. Conventional Treatment
Let us go through the major differences between stem cell therapy and conventional treatment for pulmonary fibrosis –
Differences | Stem Cell Therapy | Lung Transplant Surgery |
Nature of Treatment | This is a minimally invasive non-surgical treatment method that is administered through injections. | It is an invasive and painful surgery with high risks of treatment incompatibility. |
Source | Derived from human umbilical cord tissues (Wharton’s Jelly) that are present abundantly. | Transferred surgically from donors with healthy lungs. However, there is a lack in the number of donors for this type of surgery. |
Recovery Time | Recovery from pulmonary fibrosis depends on the patients’ conditional severity and other diseases. Also, the age and gender of the patient affect the recovery period. | It takes up to 6 months to fully recover from a lung transplant surgery. However, there is no guarantee of the success of this type of treatment method. |
Cost | Stem cell therapy is cost-effective compared to expensive surgeries. However, the cost of stem cell therapy depends on factors such as the volume of stem cells required, the type of administration method, and the type of stem cells used in the treatment. | The cost of surgeries is higher as it includes post-surgical care and medications. |
Stem Cell Treatment Procedure for Pulmonary Fibrosis
This section will give you a complete insight into the treatment methods and results of stem cell therapy for pulmonary fibrosis. So, let us find out.
Administration Methods
Stem cell injections are given to patients using the following methods –
- Intravenous infusions are administered through ventricular channels.
- Intraarticular injections are injected through local joints in the affected area.
- Intramuscular injections are applied through local muscles.
The expert doctors determine which method will be used for handling a pulmonary fibrosis patient.
Results of Treatments
Some of the positive results of stem cell therapy for pulmonary fibrosis highlights –
- Reduced inflammation of the lung tissues.
- Secretion of cytokines and paracrine factors to repair lung tissue damage.
- Improves the functions of the lungs.
- Enhances the oxygen supply to the bloodstream.
- Improves the lifespan of lung fibrosis patients.
- Decreases the accumulation of collagen in the lungs.
- Facilitates gene modification to prevent fibrosis development.
Read Also: Effectiveness of Stem Cell Therapy for Lung Diseases Explained
Advanced Therapies for Lung Fibrosis
Some of the latest medical interventions for lung fibrosis include –
- Gene therapy – Introduction of genetic materials into the cells to molecular modification that is not possible through conventional drugs.
- Mesenchymal stem cell therapy – A therapeutic treatment to repair lung epithelium through transformation into functional lung cells.
- Stem cell-based exosome therapy – Treating lung scarring through extracellular vesicles derived from stem cells.
Bottomline
Stem cells show promising results for healing several types of lung diseases including chronic obstructive pulmonary disorder, asthma, pneumonia, bronchitis, and fibrosis.
The Life Altering Stem Cell Therapy Institute is a revolutionary clinic for regenerative medicine in Mexico. Our doctors are certified to administer stem cell therapy most holistically and safely.
Try our regenerative medicine for lung disorders and breathe a sigh of relief.
Improve the capabilities of the lungs and breathe freely. Talk to our experts to find the best lung disease treatment.
Remarkable Results of Stem Cell Therapy for Glenohumeral Osteoarthritis Treatment
1 out of 3 individuals above 60 years suffer from glenohumeral osteoarthritis or shoulder arthritis.
26 percent of adults above 65 years are suffering from glenohumeral osteoarthritis. This condition mostly affects the elderly.
Glenohumeral osteoarthritis is the degeneration of cartilage in the shoulder joint. This long-term disease negatively impacts the shoulder joint. Symptoms of the disease include pain, immobility, and stiffness.
Several traditional treatment methods can provide relief from the excruciating shoulder pain. Shoulder rest, application of heat packs, pain medications, and physical therapy are conventional treatment options for this condition.
Stem cell therapy is the pinnacle of regenerative medicine for osteoarthritis and orthopedic conditions.
Let’s discuss the innovative treatment methods of stem cell therapy for shoulder pain.
Overview of Glenohumeral Osteoarthritis
The glenohumeral is the primary shoulder ball-and-socket joint. This joint facilitates the free movement of the arms. The synovial fluid helps to stabilize the rotator cuff muscles for better movement. Moreover, it allows several types of motion of the arms including elevation, flexion, extension, and internal and external rotation.
Shoulder joint cartilage breakdown causes glenohumeral osteoarthritis. It exposes the ball and socket joint. This causes friction between the bones and the joint and causes bone spurs. The bone-to-joint friction limits shoulder-related activities.
Causes
The top reasons why glenohumeral osteoarthritis develops include –
- Trauma – Dislocation, fractures, or torn muscles are some types of shoulder injuries that can develop osteoarthritis.
- Infection – Joint-related infections with negative impacts.
- Genetics – People with abnormal genes are more likely to pass down such a condition to their predecessors.
- Inflammation and Aging – Inflammatory conditions such as rheumatoid arthritis or normal signs of aging induce the breakdown of the glenohumeral joint.
- Other factors – Obesity and sports such as javelin and discuss increase injury risks to the shoulder.
Impact on Life
Pain from shoulder arthritis degrades the quality of life and restricts multiple activities. Problems indicating glenohumeral osteoarthritis are –
- Severe pain that causes discomfort and sleeping problems.
- Limited motion of the arm.
- Crepitus or clicking and snapping sounds of the shoulder due to movement.
- Depression and anxiety due to constant pain in the shoulder.
- Risks related to job performance due to limited shoulder abilities.
Conventional Treatment Limitations
Shoulder pain traditional treatment limitations highlight –
- Temporary pain relief with corticosteroid injections.
- Chances of kidney injuries or digestive ulcers with non-steroidal anti-inflammatory drugs.
- Little or no proof of improvement with dietary supplements.
- Adverse effects of opioid medications.
Stem Cell Therapy Insights for Treating Glenohumeral Osteoarthritis
Stem cell therapy is a holistic treatment method for healing injuries and diseases. This regenerative medicine promotes self-healing.
Types of Stem Cells Used for Treatment
Different types of stem cells are categorized as multipotent, pluripotent, and totipotent. The most noted types of stem cells are –
- Mesenchymal stem cells – MSCs are found in the adipose layers and human umbilical cord tissues (Wharton’s Jelly).
- Embryonic stem cells – Human embryo-derived stem cells that can transform into any type of cells.
- Hematopoietic stem cells – Adult stem cells with the ability to convert into red blood cells, white blood cells, and platelets.
- Induced pluripotent stem cells – A manually reprogrammed adult stem cell to promote cell differentiation.
Stem cells alleviate shoulder pain from different injuries and conditions such as –
- Bursitis – Inflammation of the shoulder joints due to the synovial fluid in the sacs.
- Myositis – Weakening of the shoulder muscles due to inflammation from this autoimmune disease.
- Rotator cuff injuries – Rotator cuff tears, tendonitis, and rotator cuff bursitis.
- Frozen shoulder – A painful sensation in the shoulder and neck that restricts movement.
- Parsonage-Turner syndrome – Severe shoulder pain due to a rare neurological disorder.
Read Also: How To Manage Shoulder Rotator Cuff Injuries with Stem Cell Therapy?
Role of Wharton’s Jelly-Derived MSCs for Shoulder Osteoarthritis Treatment
Stem cell therapy releases trophic factors. This reduces inflammation and accelerates cartilage regeneration. MSC therapy for glenohumeral joint osteoarthritis helps through –
- Tissue Regeneration – Transformation into glenohumeral cartilage cells to promote shoulder joint recovery.
- Inflammation Restriction – MSCs release growth factors such as cytokines and chemokines to enhance joint functions and alleviate shoulder pain by reducing inflammation.
- Long-Term Healing – Promotes the formation of blood vessels in areas of injury or disease.
Stem Cell Therapy for Shoulder Arthritis Clinical Reports
Several patients choose stem cell therapy to treat different orthopedic conditions. In this section, we will explore the results of clinical trials and case studies of patients who are successfully treated with stem cells for their reduced shoulder joint abilities.
Clinical Trials
Multiple clinical studies on patients suffering from shoulder pain indicate –
- MSCs can transform into chondrocytes or cartilage-forming cells.
- Regulate the immune system.
- Regenerate damaged cartilage in the shoulder joint.
- Prevents apoptosis or cell death.
- Prevents fibrosis.
- Improves blood supply.
Case Studies
Here are some reports from case studies –
- Case Study 1 – Chris suffered from two shoulder injuries. However, he was able to move his locked shoulder in a few minutes after the stem cell therapy injection. The patient was fully relieved from pain and immobility within 1 year of stem cell therapy.
- Case Study 2 – Jonathan had a torn rotator cuff injury but the suggested physiotherapy did not work. They tried stem cell therapy and experienced complete relief from the symptoms of the shoulder injuries. Moreover, their torn rotator cuff healed naturally.
- Case Study 3 – A 2017 study by the Journal of Orthopedic Surgery and Research highlighted that patients who chose stem cell therapy for shoulder arthritis indicated improved joint functions and imaging results after the treatment.
Read Also: How Does Stem Cell Therapy Work to Fix A Torn Rotator Cuff?
Stem Cell Therapy Vs. Traditional Treatment
Let us go through the comparative results for both types of treatment methods –
Differences | Stem Cell Therapy | Surgery |
Recovery Duration | The recovery time varies from one patient to another depending on their age, conditional severity, and other illnesses. Some patients highlight pain relief within a few hours of treatment while others can take months to fully recover. | Takes up to 2 months to recover from a shoulder osteoarthritis surgery. |
Nature of Treatment | It is a minimally invasive treatment that is administered through injections. | Surgical interventions are always invasive and painful. |
Risks of Treatment | Negligible side effects of stem cell therapy.
Slight headaches or nausea are experienced by some patients. |
Surgeries raise the chances of infections and complications. |
Cost of Treatment | A cost-effective treatment compared to surgeries. However, the cost of the treatment depends on different factors including the patient’s age, weight, height, gender, and the volume and type of stem cells needed for the therapy. | The cost of surgeries is high and includes long-term post-surgical relief medications as well. |
Stem Cell Therapy Benefits for Shoulder Pain
Well-recorded benefits of this treatment showcase the following –
- Complete pain relief from shoulder injuries, osteoarthritis, or tendonitis.
- MSCs regenerate damaged glenohumeral joint cartilage to improve the functions of the shoulder and arms.
- MSCs take much less time to administer and patients can experience quick results after the treatment.
- Stem cell therapy reduces the need for additional drugs and medications.
- Stem cells can transform into different types of cartilage to promote regeneration.
- Enhances growth factor release such as cytokines to inhibit inflammation of the joints.
- A non-surgical and minimally invasive treatment for shoulder arthritis.
Glenohumeral Osteoarthritis Treatment Procedure with Stem Cells
Shoulder arthritis treatment methods are –
Treatment Methods
Different administration methods for stem cell injections include –
- Intravenous infusions are introduced through ventricular channels.
- Intraarticular injections are applied through a local joint near the affected area.
- Intramuscular injections are injected through local muscles.
Stem cells are derived from human umbilical cord tissues and are tested in a clinical setting for maximum efficacy. MSCs are cultivated in a laboratory setting and administered in a clinical setting by certified experts.
Advancements of Stem Cells for Shoulder Joint Pain
Recent advancements in stem cell therapy for osteoarthritis highlight –
- Glenohumeral cartilage tissue regeneration through chondrocyte differentiation abilities of stem cells.
- Stem cell therapy reduces inflammation symptoms and improves immune system regulation.
- Developing stem cell-based drugs to prevent chronic diseases.
- Exploration for new sources of stem cells is being practiced.
- Application of nanotechnology to isolate and differentiate stem cells.
- Creation of stem cell scaffolds with biomaterials such as collagen, fibrin, hyaluronic acid, and gelatin.
Stem Cell Therapy for Other Orthopedic Conditions
Stem cell therapy offers remarkable treatment results for shoulder, knee, and hip osteoarthritis. Results of this treatment indicate –
- Reduction of pain and inflammation at the affected site.
- Improvement in tissue reformation to restore joint functions.
- Stoppage and reversal of arthritic effects.
- Stem cell therapy for shoulder, knee, and hip pain can improve the sleep cycle for patients.
- Eliminates the scope of surgery.
Stem Cell Therapy with Other Treatments
Stem cell therapy highlights remarkable results for orthopedic conditions including bone injuries, cartilage defects, ligament, and knee injuries.
Some of the combination methods to cure orthopedic diseases include –
- Platelet-rich plasma (PRP) and stem cell combination therapy to reduce knee pain and accelerate cartilage regeneration.
- Combination of stem cells with biomaterials such as hyaluronic acid and collagen to stimulate natural regeneration.
- Gene editing with stem cells to improve therapeutic strategies and outcomes.
Bottomline
Stem cell therapy has long-term benefits for treating orthopedic conditions. Moreover, it eliminates the chances of hospitalization and costly surgeries. Most importantly, cartilage regeneration is the primary attribute of stem cells in this condition.
Stem cell therapy relieved many patients from the symptoms of glenohumeral osteoarthritis.
The Life Altering Stem Cell Therapy Institute is a renowned American-owned clinic in Mexico providing personalized care to patients with glenohumeral osteoarthritis.
Talk to our certified stem cell doctors for personalized cell-based therapy for shoulder osteoarthritis.
Recreate new moments and live your life to the fullest with complete recovery from stem cell therapy.
How To Recover from Neurodegenerative Diseases with Stem Cell Treatment
More than 50 million people are suffering from neurodegenerative diseases. 1 out of every 3 people has a chance of developing neurological disorders.
6.2 million people alone in the US are affected by neurodegenerative disorders.
Nearly 15 percent of the global population is suffering from physical and cognitive disabilities due to neurological conditions.
Alzheimer’s and Parkinson’s are leading neurodegenerative diseases.
Neurodegenerative diseases affect the mental, heart, and autonomic functions of a person.
Most patients experience permanent symptoms from neurological diseases. These diseases destroy nerve cells and impair peripheral nervous system functions.
This blog lets us learn the benefits of non-surgical stem cell treatment. We will discuss the best alternative treatment for neurodegenerative diseases.
Overview of Neurodegenerative Diseases
Neurodegenerative diseases kill the brain cells, nerve cells, and the abilities of the nervous system. Leading causes of such diseases include genetics, habits such as alcoholism, illnesses such as stroke, and aging.
Such diseases affect each individual differently. They experience various symptoms at different stages of life. Some of the symptoms of neurodegenerative diseases are –
- Immobility and imbalance
- Abnormal walking posture
- Difficulty in swallowing
- Reduced bowel and bladder function
- Fluctuating blood pressure levels
- Sleep disturbances
- Breathing problem
- Decreased functions of the heart
Types of Neurodegenerative Diseases
In this section, we will explore the different types of neurodegenerative diseases and their impact on life.
Alzheimer’s Disease
Alzheimer’s disease is a type of dementia that causes gradual memory loss. The premature death of nerve cells in the brain impairs thinking and memory functions.
Predominant signs of this disease highlight –
- Loss of memory
- Difficulty in reading or writing
- Time and place-related confusion
- Frequent mood swings
- Chances of getting lost while wandering
- Poor judgment and bad decision-making
Common causes of Alzheimer’s disease are –
- Shrinking of blood vessels in the brain due to aging.
- Passing down the symptoms or causes of the disease through genetics.
- Environmental factors such as exposure to air pollutants.
- Hypertension, diabetes, obesity, and heart disease increase the chances of Alzheimer’s.
Parkinson’s Disease
Dopamine-producing islet cell death in the brain causes Parkinson’s. A reduction in the level of dopamine within the body causes several disabilities. It impacts the body’s balance, mobility, and ability to coordinate.
Prevalent symptoms of Parkinson’s disease highlight –
- Shaking or tremors of the legs, arms, or jaw.
- Slow movement and repeated movements with walking difficulties.
- Stiff and inflexible muscles with sudden cramps
- Loss of smell
- Excess salivation
- Mood swings and disorders such as depression
Age, genetics, environmental factors, and brain injuries can aggravate the symptoms of Parkinson’s disease. People who have Parkinson’s also suffer the risk of developing Melanoma, helicobacter pylori infection, and low levels of blood urate.
Multiple Sclerosis
Multiple sclerosis is a neurodegenerative condition that impairs the central nervous system of the patient. The brain and spinal cord are seriously affected due to the disease.
The degeneration of the myelin sheath is the primary cause of MS. Naturally, the signal transmission is reduced or blocked due to this condition.
Symptoms of multiple sclerosis include –
- Blurred vision, blind spot, and double vision
- Weakness of the muscles
- Imbalance
- Bladder and bowel dysfunction
- Memory and reasoning difficulties
Leading causes of multiple sclerosis include –
- Family history of MS genetics can be passed on to children.
- Low levels of Vitamin D
- High body mass indexing or obesity
- A common MS virus called Epstein-Barr
- Lifestyle factors such as smoking
- High level of stress and hypertension
Read Also: Benefits of Stem Cell Treatment: How To Stop the Progression of Multiple Sclerosis?
Huntington’s Disease
A type of brain disorder that slowly damages nerve cells. Huntington’s disease is usually inherited through genetics. It causes cognitive impairment and induces psychiatric symptoms. This disease can impact both children and adults based on the onset period.
Common symptoms of this disease indicate –
- Behavioral changes such as concentration problems, irritability, clumsiness, and depression.
- Problems with speech and swallowing.
- Mobility and body-balancing problems.
- Involuntary movements and fidgeting.
- Memory loss and poor judgment.
- Paranoia and hallucination.
- Obsessive-compulsive disorder and bipolar disorder.
Mutated HTT genes cause Huntington’s disease. In most cases, these abnormal genes are passed down to a child from either of the parents.
Multiple System Atrophy
Several regions of the brain deteriorate when a person is suffering from multiple system atrophy. It significantly limits the functions coordinated from those parts of the brain. Multiple system atrophy is an encapsulation of three conditions. These are striatonigral degeneration, Shy-Drager syndrome, and sporadic olivopontocerebellar atrophy.
Dysfunctional symptoms of this disease highlight –
- Reduced blood pressure levels.
- Dysfunctional bladder system.
- Erectile dysfunction in men.
- Rapid eye movement and sleeping disorders.
- Vision problems.
- Sleep apnea.
Genetics related to Parkinson’s disease and oxidative stress, environmental factors, and abnormal alpha-synuclein protein levels in the brain cells cause multiple system atrophy.
Symptoms
People who suffer from neurodegenerative diseases go through the following problems –
- Difficulty in movement – Weakness, paralysis, abnormal walking, and muscle spasms.
- Reduced mental functioning – Memory loss, confusion, and loss of concentration.
- Modified autonomic functions – Irregular blood pressure levels, disturbances of sleeping patterns, and dysfunctional bowel system.
- Difficulty speaking, stuttering, and other speech problems.
Challenges with Traditional Treatment Methods
Medical practitioners and patients face several challenges with traditional treatment methods for neurodegenerative diseases. Some of the difficulties are –
- Difficulties in drug delivery to the brain due to the non-invasive nature of the blood-brain barrier that prevents passing foreign substances to the brain.
- Lack of treatment options to heal the causes of neurodegenerative diseases. Most treatment methods only focus on managing the symptoms of neurological conditions.
- Problem in identifying the reason for cell death in the early stages of a neurodegenerative disease.
- Lack of research material related to the several pathogenic mechanisms that contribute to neurodegenerative diseases.
- The survival rate of patients with neurodegenerative diseases is very low.
- It is highly difficult to diagnose a neurodegenerative disease conclusively in the early stages.
Stem Cell Therapy for Neurodegenerative Diseases
Stem cell is a type of regenerative medicine. These cells are found within the human body and act as the repair system.
These cells are important for tissue engineering, required for stem cell therapy, applied in biochemical techniques, and stimulate the body’s natural healing process.
Stem cell therapy is highly effective in healing cardiovascular diseases, autoimmune diseases, spinal cord injuries, cancer, orthopedic conditions, and neurodegenerative diseases.
Types of Stem Cells
Different types of stem cells include –
- Adult stem cells – Found in adults, these cells replace the dead cells in the body.
- Embryonic stem cells – Derived from human embryos, these cells can transform into any type of cell.
- Mesenchymal stem cells – Found in the human umbilical cord tissues (Wharton’s Jelly), bone marrow, or body fat.
- Neural stem cells – Tissue-oriented stem cells that regenerate brain and nerve cells.
- Pluripotent stem cells – Adult stem cells with the ability to convert into any type of body cells.
Characteristics of Stem Cells
Features of stem cells highlight –
- Undivided and non-functional stem cells in the primary stages perform the actions of the cells they convert into.
- The ability of stem cells to constantly multiply and renew itself.
- Transformative abilities of MSCs enable conversion into blood, heart, brain, and nerve cells.
- Different abilities of stem cells such as multipotency, pluripotency, and totipotency help to treat different diseases and injuries.
- Anti-inflammatory actions that provide pain relief from several conditions.
- Immunomodulatory effects improve the function of the immunity system to fight infections better.
Administration Process for Stem Cell Injections
Stem cell therapy is a minimally invasive and non-surgical treatment. Let us find out the different types of administration methods for stem cells –
- Intravenous injections of mesenchymal stem cells are given through the veins.
- Intraarticular injections are given directly into the site of the pain, injury, or disease.
- Intramuscular injections are given into the surrounding muscle of the affected area.
Benefits of Stem Cell Treatment
Remarkable benefits of stem cell therapy for neurodegenerative diseases indicate –
- Replacement of damaged and dead neurons with new and replenished ones.
- Regeneration and stabilization of the neuronal network for better signal transmission.
- Reversal of neurodegeneration symptoms at the neural circuit level to improve learning and tuning abilities.
- Regeneration of damaged or lost neural tissues.
- Reinstating cognitive abilities such as attention span, information processing, memory, and thinking abilities.
- Restoration of body balance.
- Improvement in posture, mobility, and digestion.
- Secretion of neurotrophic and growth factors such as chemokines and cytokines for natural replacement of lost cells.
- Stem cells promote the regenerative abilities of neurons to improve brain functions in Alzheimer’s disease treatment.
- MSCs possess neurogenesis abilities that repair the dopamine-producing cells in the brain through stem cell therapy for Parkinson’s disease.
- MSCs have neurogenesis property enabling them to stimulate myelination or regeneration of the myelin sheath through oligodendrocyte cell differentiation.
Patient Success Stories
Mesenchymal stem cells highlight remarkable results of improvement in patients with neurodegenerative disorders. Highlights from case studies depict –
Case Studies
- Case Study 1 – Louise was the first human on the planet who successfully recovered from multiple sclerosis after getting a stem cell therapy with mesenchymal stem cells.
- Case Study 2 – A 75-year-old lady named Greta completely recovered from multiple sclerosis after two stem cell therapy sessions.
Scope of Future Improvements
Potential improvements in neurodegenerative treatment methods highlight –
- Gene therapy – Replacement of diseased or mutated genes with healthy ones.
- Precision medicine – A technique to combine neurological test results, genome sequencing, lab vitals, and imaging scans to come up with better treatment methods.
- Biomarker identification – The latest biomarkers can help to detect neurological diseases at the earliest stage.
- Stem cell therapy – A regenerative medicine that promotes natural regeneration of damaged tissues and cells.
Advancements in Stem Cell Therapy for Neurological Diseases
Breakthrough of novel stem cell therapy is a scientific and healthcare achievement. Some of the innovative advancements in stem cell therapy for treating neurodegenerative diseases highlight –
- The ability of neural stem cells and mesenchymal stem cells to transform into particular cells such as glial cells or neurons. This helps to replace neurologically damaged cells.
- Gene modification strategies are currently tested using stem cells to treat neurodegenerative diseases.
- Possibility of stem cell administration through the nasal cavity to avoid the blood-brain barrier.
- Creation of 3-D scaffolds to make a suitable environment for stem cell differentiation.
Read Also: Is Stem Cell Therapy A Cure For Neurodegenerative Diseases?
Conclusion
Accelerated production of growth factors to replace damaged neurons and slow the progression of the diseases.
The therapeutic properties of stem cells help to restore the lost functions of the brain. Also, it helps to improve the motor functions of neurodegenerative patients.
The Life Altering Stem Cell Therapy Institute is a renowned American-owned clinic with the best stem cell treatment for Alzheimer’s in Mexico.
Talk to our certified stem cell doctors to identify the best treatment for your condition.
Regain muscle strength, move freely, and make the most of your memories with stem cell therapy.
How To Recover from Neurodegenerative Diseases with Stem Cell Treatment
More than 50 million people are suffering from neurodegenerative diseases. 1 out of every 3 people has a chance of developing neurological disorders.
6.2 million people alone in the US are affected by neurodegenerative disorders.
Nearly 15 percent of the global population is suffering from physical and cognitive disabilities due to neurological conditions.
Alzheimer’s and Parkinson’s are leading neurodegenerative diseases.
Neurodegenerative diseases affect the mental, heart, and autonomic functions of a person.
Most patients experience permanent symptoms from neurological diseases. These diseases destroy nerve cells and impair peripheral nervous system functions.
This blog lets us learn the benefits of non-surgical stem cell treatment. We will discuss the best alternative treatment for neurodegenerative diseases.
Overview of Neurodegenerative Diseases
Neurodegenerative diseases kill the brain cells, nerve cells, and the abilities of the nervous system. Leading causes of such diseases include genetics, habits such as alcoholism, illnesses such as stroke, and aging.
Such diseases affect each individual differently. They experience various symptoms at different stages of life. Some of the symptoms of neurodegenerative diseases are –
- Immobility and imbalance
- Abnormal walking posture
- Difficulty in swallowing
- Reduced bowel and bladder function
- Fluctuating blood pressure levels
- Sleep disturbances
- Breathing problem
- Decreased functions of the heart
Types of Neurodegenerative Diseases
In this section, we will explore the different types of neurodegenerative diseases and their impact on life.
Alzheimer’s Disease
Alzheimer’s disease is a type of dementia that causes gradual memory loss. The premature death of nerve cells in the brain impairs thinking and memory functions.
Predominant signs of this disease highlight –
- Loss of memory
- Difficulty in reading or writing
- Time and place-related confusion
- Frequent mood swings
- Chances of getting lost while wandering
- Poor judgment and bad decision-making
Common causes of Alzheimer’s disease are –
- Shrinking of blood vessels in the brain due to aging.
- Passing down the symptoms or causes of the disease through genetics.
- Environmental factors such as exposure to air pollutants.
- Hypertension, diabetes, obesity, and heart disease increase the chances of Alzheimer’s.
Parkinson’s Disease
Dopamine-producing islet cell death in the brain causes Parkinson’s. A reduction in the level of dopamine within the body causes several disabilities. It impacts the body’s balance, mobility, and ability to coordinate.
Prevalent symptoms of Parkinson’s disease highlight –
- Shaking or tremors of the legs, arms, or jaw.
- Slow movement and repeated movements with walking difficulties.
- Stiff and inflexible muscles with sudden cramps
- Loss of smell
- Excess salivation
- Mood swings and disorders such as depression
Age, genetics, environmental factors, and brain injuries can aggravate the symptoms of Parkinson’s disease. People who have Parkinson’s also suffer the risk of developing Melanoma, helicobacter pylori infection, and low levels of blood urate.
Multiple Sclerosis
Multiple sclerosis is a neurodegenerative condition that impairs the central nervous system of the patient. The brain and spinal cord are seriously affected due to the disease.
The degeneration of the myelin sheath is the primary cause of MS. Naturally, the signal transmission is reduced or blocked due to this condition.
Symptoms of multiple sclerosis include –
- Blurred vision, blind spot, and double vision
- Weakness of the muscles
- Imbalance
- Bladder and bowel dysfunction
- Memory and reasoning difficulties
Leading causes of multiple sclerosis include –
- Family history of MS genetics can be passed on to children.
- Low levels of Vitamin D
- High body mass indexing or obesity
- A common MS virus called Epstein-Barr
- Lifestyle factors such as smoking
- High level of stress and hypertension
Read Also: Benefits of Stem Cell Treatment: How To Stop the Progression of Multiple Sclerosis?
Huntington’s Disease
A type of brain disorder that slowly damages nerve cells. Huntington’s disease is usually inherited through genetics. It causes cognitive impairment and induces psychiatric symptoms. This disease can impact both children and adults based on the onset period.
Common symptoms of this disease indicate –
- Behavioral changes such as concentration problems, irritability, clumsiness, and depression.
- Problems with speech and swallowing.
- Mobility and body-balancing problems.
- Involuntary movements and fidgeting.
- Memory loss and poor judgment.
- Paranoia and hallucination.
- Obsessive-compulsive disorder and bipolar disorder.
Mutated HTT genes cause Huntington’s disease. In most cases, these abnormal genes are passed down to a child from either of the parents.
Multiple System Atrophy
Several regions of the brain deteriorate when a person is suffering from multiple system atrophy. It significantly limits the functions coordinated from those parts of the brain. Multiple system atrophy is an encapsulation of three conditions. These are striatonigral degeneration, Shy-Drager syndrome, and sporadic olivopontocerebellar atrophy.
Dysfunctional symptoms of this disease highlight –
- Reduced blood pressure levels.
- Dysfunctional bladder system.
- Erectile dysfunction in men.
- Rapid eye movement and sleeping disorders.
- Vision problems.
- Sleep apnea.
Genetics related to Parkinson’s disease and oxidative stress, environmental factors, and abnormal levels of alpha-synuclein protein in the brain cells cause multiple system atrophy.
Symptoms
People who suffer from neurodegenerative diseases go through the following problems –
- Difficulty in movement – Weakness, paralysis, abnormal walking, and muscle spasms.
- Reduced mental functioning – Memory loss, confusion, and loss of concentration.
- Modified autonomic functions – Irregular blood pressure levels, disturbances of sleeping patterns, and dysfunctional bowel system.
- Difficulty speaking, stuttering, and other speech problems.
Challenges with Traditional Treatment Methods
Medical practitioners and patients face several challenges with traditional treatment methods for neurodegenerative diseases. Some of the difficulties are –
- Difficulties in drug delivery to the brain due to the non-invasive nature of the blood-brain barrier that prevents passing foreign substances to the brain.
- Lack of treatment options to heal the causes of neurodegenerative diseases. Most treatment methods only focus on managing the symptoms of neurological conditions.
- Problem in identifying the reason for cell death in the early stages of a neurodegenerative disease.
- Lack of research material related to the several pathogenic mechanisms that contribute to neurodegenerative diseases.
- The survival rate of patients with neurodegenerative diseases is very low.
- It is highly difficult to diagnose a neurodegenerative disease conclusively in the early stages.
Stem Cell Therapy for Neurodegenerative Diseases
Stem cell is a type of regenerative medicine. These cells are found within the human body and act as the repair system.
These cells are important for tissue engineering, required for stem cell therapy, applied in biochemical techniques, and stimulate the body’s natural healing process.
Stem cell therapy is highly effective in healing cardiovascular diseases, autoimmune diseases, spinal cord injuries, cancer, orthopedic conditions, and neurodegenerative diseases.
Types of Stem Cells
Different types of stem cells include –
- Adult stem cells – Found in adults, these cells replace the dead cells in the body.
- Embryonic stem cells – Derived from human embryos, these cells can transform into any type of cell.
- Mesenchymal stem cells – Found in the human umbilical cord tissues (Wharton’s Jelly), bone marrow, or body fat.
- Neural stem cells – Tissue-oriented stem cells that regenerate brain and nerve cells.
- Pluripotent stem cells – Adult stem cells with the ability to convert into any type of body cells.
Characteristics of Stem Cells
Features of stem cells highlight –
- Undivided and non-functional stem cells in the primary stages perform the actions of the cells they convert into.
- The ability of stem cells to constantly multiply and renew itself.
- Transformative abilities of MSCs enable conversion into blood, heart, brain, and nerve cells.
- Different abilities of stem cells such as multipotency, pluripotency, and totipotency help to treat different diseases and injuries.
- Anti-inflammatory actions that provide pain relief from several conditions.
- Immunomodulatory effects improve the function of the immunity system to fight infections better.
Administration Process for Stem Cell Injections
Stem cell therapy is a minimally invasive and non-surgical treatment. Let us find out the different types of administration methods for stem cells –
- Intravenous injections of mesenchymal stem cells are given through the veins.
- Intraarticular injections are given directly into the site of the pain, injury, or disease.
- Intramuscular injections are given into the surrounding muscle of the affected area.
Benefits of Stem Cell Treatment
Remarkable benefits of stem cell therapy for neurodegenerative diseases indicate –
- Replacement of damaged and dead neurons with new and replenished ones.
- Regeneration and stabilization of the neuronal network for better signal transmission.
- Reversal of neurodegeneration symptoms at the neural circuit level to improve learning and tuning abilities.
- Regeneration of damaged or lost neural tissues.
- Reinstating cognitive abilities such as attention span, information processing, memory, and thinking abilities.
- Restoration of body balance.
- Improvement in posture, mobility, and digestion.
- Secretion of neurotrophic and growth factors such as chemokines and cytokines for natural replacement of lost cells.
- Stem cells promote the regenerative abilities of neurons to improve brain functions in Alzheimer’s disease treatment.
- MSCs possess neurogenesis abilities that repair the dopamine-producing cells in the brain through stem cell therapy for Parkinson’s disease.
- MSCs have neurogenesis property enabling them to stimulate myelination or regeneration of the myelin sheath through oligodendrocyte cell differentiation.
Patient Success Stories
Mesenchymal stem cells highlight remarkable results of improvement in patients with neurodegenerative disorders. Highlights from case studies depict –
Case Studies
- Case Study 1 – Louise was the first human on the planet who successfully recovered from multiple sclerosis after getting a stem cell therapy with mesenchymal stem cells.
- Case Study 2 – A 75-year-old lady named Greta completely recovered from multiple sclerosis after two stem cell therapy sessions.
Scope of Future Improvements
Potential improvements in neurodegenerative treatment methods highlight –
- Gene therapy – Replacement of diseased or mutated genes with healthy ones.
- Precision medicine – A technique to combine neurological test results, genome sequencing, lab vitals, and imaging scans to come up with better treatment methods.
- Biomarker identification – The latest biomarkers can help to detect neurological diseases at the earliest stage.
- Stem cell therapy – A regenerative medicine that promotes natural regeneration of damaged tissues and cells.
Advancements in Stem Cell Therapy for Neurological Diseases
Breakthrough of novel stem cell therapy is a scientific and healthcare achievement. Some of the innovative advancements in stem cell therapy for treating neurodegenerative diseases highlight –
- The ability of neural stem cells and mesenchymal stem cells to transform into particular cells such as glial cells or neurons. This helps to replace neurologically damaged cells.
- Gene modification strategies are currently tested using stem cells to treat neurodegenerative diseases.
- Possibility of stem cell administration through the nasal cavity to avoid the blood-brain barrier.
- Creation of 3-D scaffolds to make a suitable environment for stem cell differentiation.
Read Also: Is Stem Cell Therapy A Cure For Neurodegenerative Diseases?
Conclusion
Accelerated production of growth factors to replace damaged neurons and slow the progression of the diseases.
The therapeutic properties of stem cells help to restore the lost functions of the brain. Also, it helps to improve the motor functions of neurodegenerative patients.
The Life Altering Stem Cell Therapy Institute is a renowned American-owned clinic with the best stem cell treatment for Alzheimer’s in Mexico.
Talk to our certified stem cell doctors to identify the best treatment for your condition.
Regain muscle strength, move freely, and make the most of your memories with stem cell therapy.
How To Manage Post-Meniscectomy Knee Pain with Stem Cell Therapy
More than 50 percent of men above the age of 70 years and 16 percent of women over 50 years experience meniscus tears.
Nearly 60 people out of 100,000 population are prone to go through knee meniscus tears during their lifetime.
The meniscus is a C-shaped knee cartilage that also acts like a shock absorber. These are rubbery disks that provide cushioning to the knee joints.
Sudden and sharp reflexes such as twisting or rotating of the knees can cause meniscal tears.
In this blog, we will explore the possibilities of post-meniscectomy pain relief and alternatives to knee surgery for meniscus tears.
Overview of Post-Meniscectomy Syndrome
This is a condition that affects people who underwent meniscectomy surgery. It is a type of surgery to remove the damaged meniscus from the knees.
Symptoms
Signs of post-surgical complications include –
- Progressive limb deformity
- Narrow joint spacing
- Chondral and subchondral changes
- Excruciating pain for some weeks after the surgery
Conventional Treatments
Conventional treatment options for a torn meniscus are –
- Rest, elevation of the affected knee, and application of an ice pack on the injured area.
- Medications such as ibuprofen to reduce chronic knee pain of the knee. However, it is best not to consume anti-inflammatory medicines for up to 7 days before stem cell therapy.
- Application of knee braces or bandages for extra support and pain relief.
- Basic stretching exercises to reduce knee pain.
- A microsurgery to repair the torn meniscus.
Pain Relief Techniques
Some ways how torn meniscus patients can experience relief from pain are –
- Short-term pain relief with non-surgical methods
- Meniscus scaffolds to provide mid-term knee support
- Long-term relief with allograft transplantation
- Isolated cartilage repair offers better results if the menisci are reconstructed
Overview of Knee Meniscus Tear
Meniscal tear is a knee injury that affects the knee joints and cartilage. Signs of meniscus tears include pain, swelling, and stiffness at the affected spot. Moreover, it can restrict the mobility of a person.
Causes
Forcefully twisting the knees can cause meniscus damage. The chances of meniscal injuries increase when the whole weight of the body is put on the knees. Common causes of this type of injuries are –
- Heavy lifting
- Excessive running or sports activities
- Degenerative diseases of the knee
- Misalignment of the knee
- Previous injuries or trauma that directly impacts the knees
- Age-related conditions
Limitations of Traditional Post-Meniscectomy Syndrome Treatment
Limitations and side effects of traditional treatment for post-meniscectomy syndrome are –
- Decreased muscle strength
- Reduced range of motion
- Altered perception of bodily movements
- Abnormal walking
- Biochemical factors increase the symptoms of osteoarthritis
Traditional Pain Management Methods
Traditional pain management for post-meniscectomy syndrome are –
- Rest, application of ice packs, pain medication, physical therapy, and anti-inflammatory drugs.
- A rehabilitation program for up to 24 weeks to let the patient develop new meniscus tissues.
- Scaffolds of the meniscus that offer mid-term pain relief after meniscectomy.
- Joint replacements are suggested for later stages of the surgery if the patient does not get fruitful results.
Need for Innovative Treatment
It is possible to repair a fully torn meniscus without surgeries. However, complications may arise if the patient undergoes the wrong treatment. Sometimes, there is no alternative to knee replacement surgery. However, the advent of stem cell therapy and the latest scientific technology makes it possible to repair a torn meniscus without surgeries. This significantly reduces the chances of post-surgical complications.
Some of the innovative treatment options for post-meniscectomy syndrome include –
- Hyaluronic acid and cortisone injections are given to the affected joints.
- Platelet-rich plasma (PRP) therapy to naturally heal and repair.
- Stem cell therapy promotes natural regeneration of the damaged meniscus.
Read Also: How Successful is Sciatica Treatment with Stem Cell Therapy
Stem Cell Treatment for Post-Meniscectomy Syndrome
Stem cell therapy for knee meniscus tear treatment is a promising alternative. Let us explore the features of how stem cells promote natural meniscus repair without surgeries –
- Stem cells can identify and transform into chondrocytes which are cartilage cells needed to repair a damaged meniscus.
- MSCs migrate to the site of the injury or disease to start fixing the core cause of the issue.
- Stem cells accelerate the secretion of cytokines and chemokines that help to heal a damaged meniscus.
- Stem cells release growth factors that promote tissue and cell regeneration.
- MSCs are anti-inflammatory, immunomodulatory, and regenerative allowing self-healing of damaged tissues.
Characteristics of Mesenchymal Stem Cells
Mesenchymal stem cells (MSCs) are derived from human umbilical cord tissues (Wharton’s Jelly). These cells act as the body’s repair system. Some of the unique properties of MSCs are –
- Undivided in the primary stages with no specific functions.
- Ability to consistently renew and multiply stem cells required for healing.
- Has the potential to transform into any type of stem cell.
- Stem cells are collected from different parts of the body and are differently potent and highlight multiple regenerative abilities.
- MSCs are anti-inflammatory and prevent the chances of several diseases.
- Stem cells can improve the actions of the immune system and help fight infections better.
Benefits of Treatment
Some of the benefits of stem cell therapy for knee pain are –
- MSCs transform into cartilage cells that promote meniscus regeneration.
- Alleviates knee pain and promotes tissue recovery.
- The ability of MSCs to migrate to the area of inflammation, injury, or disease.
- Accelerates self-healing through cytokines and chemokines secretion.
- MSCs are abundantly accessible.
- Stem cells prevent inflammation of the damaged meniscus tissues and cells.
- MSCs promote cell activation in the area of damage.
- Mesenchymal stem cells quickly multiply when they come in contact with damaged tissues or cells.
- Stem cells promote the production of beta 1 growth factors.
- MSC migration is beneficial to regrow connective tissues.
- Stem cells accelerate blood vessel formation.
- Stem cells can easily transform into meniscal tissues.
Administration Procedure
Stem cells are administered non-surgically using minimally invasive methods. Common application methods include –
- Intravenous infusions are injected through the veins.
- Intraarticular injections are given directly at the injury site.
- Intramuscular injections are introduced through an appropriate muscle near the affected region.
The doctors determine the administration process after evaluating the patient’s age, gender, and severity of the meniscal tear.
Read Also: Discover the Future of Healing: Regenerative Medicine and Stem Cell Therapy in Miami
Patient Success Stories
Stem cell therapy is a highly successful treatment for repairing meniscus tears. Patient case study results highlight –
Case Studies
- Case Study 1 – A patient highlighted no signs of back, hip, or knee pain after only 1 session of stem cell therapy.
- Case Study 2 – Another patient had improved mobility after attending the second session of their stem cell treatment.
- Case Study 3 – An athlete highlighted up to 40 percent improvement in their knee strength 3 months after their stem cell therapy.
- Case Study 4 – A patient was given injections of mesenchymal stem cells after a partial meniscectomy surgery. The patient did not experience any pain for up to 2 years after the therapy.
Scope of Future Improvements
Recent research related to knee joint regeneration and meniscus repair therapy without surgery highlights –
- MSCs can fully regenerate a torn meniscus.
- Synovial MSCs in the knee joints can promote self-healing for knee injuries.
- MSCs derived from the bone marrow are directly injected at the knee injury site.
Phenomenal advancements in world-class technology paved the way for stem cell experts to integrate this regenerative therapy with surgical interventions. Some common knee improvement surgeries using stem cells include –
- A non-surgical stem cell transplant injection that repairs damaged tissues and cells.
- Stem cell injections can be applied directly to the lesion, with a scaffold, or through channels made in the veins.
Advancements in Stem Cell Therapy for Other Orthopedic Conditions
The transformation of MSCs into mesodermal tissues helps to form bones, tendons, muscles, cartilage, and ligaments. Let us find out how stem cells can heal orthopedic conditions are –
- Stem cell scaffolds using tri-calcium phosphate for healing bone defect traumas.
- Stem cell spinal fusions to assist peripheral nerve surgery.
- Reverse the symptoms and prevent the causes of intervertebral disc degeneration.
- MSCs can replace joint surgeries with three-dimensional scaffolds.
- Heal articular cartilage damage of the meniscus.
Conclusion
It is imperative to know that stem cells cannot regrow a new meniscus. So, patients who do not have a meniscus cannot benefit from stem cell therapy. However, patients who have an injured meniscus can significantly benefit from this treatment as it promotes natural healing.
The Life Altering Stem Cell Therapy Institute is a renowned clinic in Mexico with world-class doctors and infrastructure.
Talk to us today to learn more about the benefits and results of our stem cell treatment for meniscus tears. We not only help to repair your damaged knee joint but also prepare you to return to regular activities. Bid goodbye to chronic knee pain forever!
How Successful is Sciatica Treatment with Stem Cell Therapy
Nearly 10-40 percent of the global population between the age of 50-60 years suffer from sciatica. About 5 percent of the entire population is diagnosed with this disease every year.
The human body’s largest nerve is the sciatic nerve. It is located in the lower spine and continues down through the back of the thighs up to the bottom of the foot.
This nerve has sensory and motor functions. It connects the brain with the skin and the leg muscles.
Sciatica is a condition that happens when the sciatic nerve is negatively affected. It sends pain signals to the brain even though there are no external injuries.
We will briefly explain the disease and explore the best treatment methods for sciatica using stem cells in 2024.
Symptoms of Sciatica and Impact on Life
The sciatica symptoms are different for every patient. Burning sensations, aching pain in the back, and bowel movement problems are primary signs. Other symptoms include a feeling of numbness in the affected area and weakened leg muscles.
It severely impacts the quality of life. Patients with sciatica can experience difficulty in moving, sitting, driving, or playing sports.
Conventional Sciatica Treatment vs Trending Therapies
Traditional treatments for relieving sciatica pain include –
- Application of heat pad or cold packs on the back
- Complete rest for a few days
- Stretching the hamstrings
- Chiropractic practices
- Lumbar or hip braces
- Pain reliever medications such as ibuprofen
- Surgery is the only option for patients with severe sciatica symptoms
Emerging therapies for sciatica are –
- Pulsed radiofrequency – High-frequency energy is passed through the brain to reduce pain signals in this type of minimally invasive procedure. This method is combined with epidural steroid injections to reduce signs of disability.
- Transcutaneous electrical nerve stimulation – Electrical pulses are passed through the affected area in this non-invasive treatment.
- Acupuncture – A scientific approach to alleviate the pain and numbness due to sciatica.
- Micro-pellets – A rice-sized micro-pellet is injected around the inflamed nerve. This pellet contains clonidine which reduces pain signals.
Stem Cell Therapy: A Cutting Edge Treatment in 2024
Stem cells can reinstate the body’s self-healing abilities. It is an ideal medical intervention to repair damaged tissues. Stem cells are used to treat sciatica-related back pain through direct injections in the affected area or the surrounding tissues. These cells can transform into blood cells, brain cells, nerve cells, and joint tissues.
These are undifferentiated cells that can identify and transform into different types of cells. This innovative therapy can improve the immune system and reduce inflammation. Most importantly, it stimulates natural tissue regeneration and enhances the overall quality of life.
Overview of Sciatica: Causes and Challenges
Let us find out the symptoms and causes of sciatica.
What is Sciatica?
Sciatica is a condition in which the sciatic nerve is affected. Herniated discs, bone overgrowth, and external pressure on the lumbar spine nerve roots cause excruciating pain.
The pain related to this condition lasts up to 6 weeks. Surgery may be necessary if the pain does not disappear within this time. People who have lumbar spinal stenosis or spondylolisthesis can also develop sciatica.
Read Also: Stem Cell Therapy: A Non-surgical Alternative To Spinal Stenosis
Causes
Several factors can impact the sciatic nerve and cause sciatica. Common causes are –
- Herniated disc – Dislocation of the herniated disc causes pain and pressure in the lower back that can transcend into sciatica.
- Spinal stenosis – The narrowing of the spinal canal that exerts high pressure on the sciatic nerves.
- Osteoarthritis – This is an age-related disease that can aggravate the sciatic nerve pain.
- Bone spurs – Spurs in the bone due to arthritic conditions that pinches the sciatic nerves.
- Spondylolisthesis – Misalignment of the vertebrae induces sciatic nerve problems.
- Pelvic injuries – Injuries and fractures in the pelvic region can stimulate sciatica pain.
Traditional Treatment Challenges
Traditional treatments for sciatica do not provide conclusive results to improve the symptoms of the disease. Some of the challenges in the traditional treatment method include –
- Little or no improvements in pain relief and functional abilities have been noted for patients who are suggested bed rest. Therefore, long-term bed rest for sciatica is no longer recommended by doctors.
- Analgesics, muscle relaxants, and non-steroidal anti-inflammatory drugs are less effective than a placebo to provide relief from sciatica symptoms.
- No evidence of positive results is recorded for short-term pain relief from corticosteroid injections for sciatica.
- Physical therapy does not highlight better results for sciatica improvement compared to bed rest.
Need for Innovative Sciatica Treatments in 2024
The possibility of side effects is high in conventional treatment methods. Moreover, the treatment may not be effective. Some of the reasons why there is a need for innovative treatments are –
- Rising cases of sciatica are influenced by degenerative disc diseases and lifestyle factors such as obesity.
- Limitations and temporary actions of conservative therapies, inconsistent outcomes of invasive surgeries, and side effects of sciatica pain management options.
- Increased demand for best non-surgical options for sciatica.
- Integrated approaches combine conventional treatment with advanced therapies for better results.
- The inability of current treatment methods to address the underlying issues related to sciatica.
Sciatica Treatment Review for 2024
This section provides a clinical overview of conventional sciatica treatment.
Prescriptions Drugs and Medications
Over-the-counter medications and prescription drugs for treating sciatica include –
- Tylenol is an over-the-counter medicine suggested for pain relief. These help to reduce sciatica-related inflammation.
- Prescribed muscle relaxants such as Lioresal and Zanaflex. These medicines prevent muscle spasms.
- Nerve pain medication such as Lyrica and Neurontin. These help to manage nerve pain in the neck and the back.
- Antidepressants such as duloxetine. It prevents spine-related nerve pain.
- A short course of corticosteroids.
Physical Therapy and Lifestyle Alterations
Physical therapy and lifestyle adjustments help sciatica patients get some relief from the symptoms. Some of the therapies and adjustments for managing sciatica are –
- Physical therapy – Targeted and personalized exercises to stretch the muscles of the lower back, hips, abdomen, and thigh.
- Lifestyle adjustments such as regular exercising and maintaining a good posture could relieve the pain associated with sciatica.
Effects of Cortisone Injections
Cortisone injections are effective in providing temporary pain relief from the symptoms of sciatica. However, there are some complications and long-term side effects of this treatment. Let us check them –
- Pain relief – Some patients experience immediate effects of the injections while others may need to wait a few days to experience the treatment benefits.
- Side effects – Complications related to this injection include pain at the site of administration, swelling, bruising, increased blood sugar levels, skin discoloration, infections, injury to the blood vessels, breakdown destruction of surrounding tissues, and skeleton degeneration.
NOTE: Patients should not exceed more than 3-4 cortisone injections in 1 year.
Risk and Cost of Surgery
Surgeries are effective in relieving sciatica pain. However, it also invites many risks and side effects. These include –
- Risks related to nerve damage, infections, tissue scars, excessive bleeding, and failed back surgery syndrome.
- It takes a longer time to recover from surgeries. The recovery period is increased if the patient has additional health issues. The overall recovery time from surgeries takes up to 2-4 weeks.
- Surgeries are more expensive compared to non-surgical treatments.
- Sciatica pain can resurface after 4 years or more from the surgery.
- The surgery costs for sciatica depend on the location of the clinic, the expertise of the doctor, and the type of surgery.
Limitations of Traditional Sciatica Treatment
Several limitations are recorded for conventional sciatica treatments. Some of these are –
- Bed rest – Not as effective in relieving pain and can worsen the condition.
- Medications – Analgesics do not provide long-term relief while antiepileptics are considered harmful for such conditions.
- Steroidal injections relieve patients from pain related to sciatica for the short term while causing side effects such as skin thinning as well.
- Surgery risks include nerve injuries, heart attacks, and infections.
Stem Cell Therapy for Sciatica: Treatment Breakthroughs in 2024
In this section, we will show you the latest sciatica treatment methods in 2024.
How Do Stem Cells Work?
Stem cells are the primitive cells of the body that also act as the repair system.
There are different types of stem cells. Some of them include –
- Embryonic stem cells – These are derived from human embryos and can transform into any type of cell in the body.
- Adult stem cells – These cells replace dying cells in the body.
- Pluripotent stem cells – A type of adult stem cells that can transform into other types of cells in the body.
- Mesenchymal stem cells – MSCs are found in the human umbilical cord tissues, bone marrow, and body fat.
- Multipotent stem cells – Such cells originate from different parts of the body including the placenta, tooth, and adipose tissues.
- Neural stem cells – Tissue-specific stem cells that regenerate brain and neuron cells.
The following characteristics determine the actions of stem cells in repairing and regenerating damaged tissues and cells –
- Dysfunctional – Undivided stem cells do not have any specific functions and perform the actions of a cell type they transform into.
- Self-regenerative – Stem cells divide and renew itself consistently.
- Transformative – Stem cells can differentiate and transform into different types of body cells.
- Potency – Stem cells possess different abilities. This means their effectiveness varies based on the number of cells they regenerate or repair.
- Anti-inflammatory – Stem cells can limit the inflammatory actions within the body to eliminate a wide range of diseases and heal injuries.
- Immunomodulatory – Stem cells can enhance the performance of the immune system and protect the body from injuries, infections, and diseases.
Stem Cell Treatment for Nerve Pain and Tissue Regeneration
Let us show you how stem cell therapy promotes nerve and tissue regeneration –
- Stem cells release trophic factors to speed up the body’s regenerative abilities.
- The cells secrete extracellular vesicles also known as exosomes that reduce inflammation and regulate genes.
- Stem cells regenerate the axonal myelin sheath.
- Formation of new blood vessels.
- Stem cells modulate the immune system.
- Stem cells accelerate the release of chemokines and cytokines.
Stem Cell Therapy Success Rates of Clinical Trials for Sciatica
The success rates and clinical trials for sciatica pain relief using stem cells highlight –
- Extracellular vesicles or exosomes derived from stem cells can improve the formation of nerve vessels and enhance neurological functions.
- Mesenchymal stem cells (MSCs) derived from human umbilical cord tissues (Wharton’s) highly repair sciatic nerve injuries.
- 90 percent of patients who are treated with conservative methods for herniated lumbar disc-related sciatica recover within 4 months. Similarly, surgical interventions highlight that less than 50 percent of patients recover from sciatica symptoms after surgery.
Administration Procedure for Stem Cell Injections
Stem cells are administered in a minimally invasive and non-surgical method. Treatment methods for sciatica using stem cell injections include –
- Intravenous (IV) infusions – Stem cell injections are given through the veins.
- Intraarticular injections – These types of injections are given directly at the site of the pain.
- Intramuscular injections – Stem cells are introduced through muscular injections for this type of treatment.
Stem Cell Therapy and Traditional Treatment Comparison
We will give you a brief overview of how stem cells treat sciatica compared to surgical options for sciatica treatment in this section.
Stem Cells vs. Surgery: The Better Option
The differences between stem cell therapy and surgery for sciatica treatment are –
- Stem Cell Therapy – This treatment addresses the root cause of sciatica. Therefore, the therapy helps to provide long-term relief from the symptoms of the condition. Furthermore, it is a minimally invasive and non-surgical sciatica treatment method that reduces the risks of nerve damage and accelerates tissue regeneration.
- Surgery – Surgeries are invasive and increase the risk of post-surgical complications such as excessive blood loss or nerve injuries. Moreover, it takes longer to recover from surgeries compared to stem cell therapy. However, surgeries provide better pain relief and functional improvements for up to 1 year compared to non-surgical treatments.
NOTE: The age of the patient, the severity of sciatica, and the number of treatments they explored will determine the best treatment option for them. Even though it is a personal choice, stem cell therapy is better equipped to fight sciatica symptoms without any surgical incisions and provide long-term results as well.
Read Also: Stem Cell Therapy: A Revolutionary Alternative to Invasive Surgery
Cost-Effectiveness of Stem Cell Therapy in 2024
Multiple factors determine the cost-effectiveness of stem cell therapy in 2024. These are –
- Age of the patient
- Weight, height, and gender of the patient
- Clinic location
- Type of stem cells used for treatment
- The dosage required for the patient
- Unidentified expenses
- Additional medication conditions
- Method of administration
Reduced Recovery Time
Stem cells promote faster recovery and minimum downtime to help patients return to regular life and activities at the earliest.
The treatment process is completed within 30-60 minutes. However, patients experience the results of the treatment at different intervals. It depends on their age and condition. Nevertheless, most patients experience recovery within a week of the stem cell therapy.
Reduced Risks and Safety of Stem Cell Therapy
Some of the benefits of stem cell therapy in reducing the complications related to surgeries include –
- Stem cell therapy is given through one injection of infusion making it less invasive to surgical incisions.
- Stem cell therapy offers better results compared to traditional treatment while reducing the risks related to surgeries as well.
- Patients can swiftly recover after a stem cell therapy session compared to surgeries. For example, a patient can resume their regular life one day after stem cell therapy while it may take weeks or months for patients to return to normal life after surgery.
- Stem cells promote the natural regeneration of tissues and cells while surgeries focus on removing damaged tissues and cells.
- Sciatica stem cell injections are free from the risk of developing deep vein thrombosis.
- There are no risks of nerve injuries in minimally invasive stem cell therapy compared to surgical incisions.
Success Stories from Patients in 2024
Several patients who were treated with stem cell therapy for sciatica highlighted the following results –
- Improvement in muscle strength
- Decreased neuropathic pain
- Improved mobility
Sciatica Recovery Stories Using Stem Cells
Here are some case studies of patients who tried stem cell therapy and have been living better lives since.
Case Study 1 –
A patient from Australia was treated for sciatica and they explained how they did not feel any pain during the treatment. Most importantly, they can resume regular activities and the signs of their back pain have completely disappeared after the stem cell therapy.
Case Study 2 –
An Icelandic patient got our stem cell therapy to treat back pain and a year later they say there are no signs of the pain anymore. The patient is extremely happy with the improvement in their overall quality of life.
Testimonials
Hear directly from patients who are significantly relieved from sciatic nerve pain after trying stem cell therapy.
Testimonial 1
- Edward Cullen – I came from California to Mexico after I heard about the non-surgical and cost-effective stem cell treatment for sciatica. I have been bearing pain and discomfort for the last 4 weeks and the treatment helped me get back to regular life within a week. Highly recommended for anyone who values a holistic and scientifically-approved non-invasive treatment method.
Testimonial 2
- Jacob Fatu – I am a professional wrestler and recently had a hip injury. My colleague immediately suggested stem cell therapy. I did my research and connected with the best stem cell clinic in Mexico. Thanks to their latest equipment and friendly doctors, I could return to sports within a few weeks after the treatment. Thankfully, I did not even have to go through any surgeries!
Scope of Future Improvements
Stem cells highlight long-term improvements for sciatica patients through –
- Replacing damaged cells
- Reducing inflammation
- Regenerating tissues and cells
- Repairing damaged cartilage
- Enhancing myelin sheath formation of the neuron axons
- Accelerating neurotrophic activities to maintain the nervous system
How To Confirm if Stem Cell Therapy is the Right Option
Let us highlight who is eligible to receive stem cell therapy in this section.
Eligibility for Stem Cell Therapy
An ideal candidate for stem cell therapy for sciatica should highlight the following features –
- Patients should have good health and a body that can tolerate stem cell therapy.
- Unwell people and ones who live an unorthodox lifestyle may not benefit from stem cell therapy.
- Patients who are experiencing tissue degeneration are good candidates for stem cell therapy.
- If a patient is suffering from sciatica and found no improvement in their condition after trying conventional treatment.
- A patient who went through surgery and is experiencing post-surgical complications related to back pain.
- Patients who are suggested to try surgery also make ideal candidates for the therapy.
Preparation for Treatment
Pre-procedure preparation before stem cell therapy for sciatica includes –
- Doctor’s consultation to finalize if stem cell therapy is the right option for the patient.
- Stop taking any medicines that thin the blood such as Heparin or Plavix.
- Avoid anti-inflammatory medicines for 7 days before the stem cell therapy.
- Drink up to 64 ounces of water regularly for 2 days before the therapy.
During the therapy, patients can expect –
- Stem cell injections are administered directly at the location of the injury or through intravenous infusions in a non-surgical setup.
- Imaging tests to identify the best administration method and location for stem cells.
- A quick recovery time and reduced back and hip pain using stem cell therapy.
Risks and Side Effects
Patients who want to get stem cell therapy for sciatica should be aware of the following risks and side effects –
- Side effects include fatigue, chills, headache, low-grade fever, and nausea.
- Risks include tumors, rejection of the immune system, infections due to incorrect administration methods, interactions of stem cells with certain medicines, the overall cost of stem cell therapy, and the lack of insurance coverage options for the treatment.
Post-Treatment Care and Rehabilitation
Stem cell therapy does not end after the injections are administered. Healthcare professionals conduct timely follow-up sessions with the patient once the treatment is completed. Follow-up activities include –
- Recalibrating doctor’s instructions
- Avoid anti-inflammatory drugs as long as instructed
- Reintroduce movement gradually
- Avoid high-energy activities as long as advised
- Engaging in gentle exercises such as stretching
The Future of Sciatica Treatment with Stem Cell Therapy
Get an overview of the possibilities of stem cell therapy in managing sciatica pain and providing long-term relief.
New Technology and Research
Recent research and stem cell innovations for sciatica treatment include –
- Harvesting stem cells from umbilical cord tissues takes less time compared to deriving embryonic stem cells.
- Mesenchymal stem cells (MSCs) promote pain relief.
- Magnetic targeting is used to deliver stem cells to injured nerves in a non-invasive method.
- Combination of pulsed radiofrequency with stem cell injections for better outcomes.
Advancements of Stem Cell Therapy for Other Spinal Conditions
Advancements in stem cell therapy for healing spinal cord injuries and diseases include –
- Nerve cell recovery through damaged neuron replacement and creating a microenvironment to reconnect nerve fibers.
- Regenerate tissues and cells and improve overall functions of the organs without any surgical interventions.
- Stem cells can heal injuries that occur during spine injuries.
Role of Regenerative Medicine: Stem Cells for Chronic Back Pain Management
Stem cells are regenerative medicine that offers a personalized treatment approach for sciatica in the following ways –
- Non-surgical treatment – Platelet-rich plasma (PRP) and stem cell therapy are non-invasive alternative treatments for sciatica pain compared to surgeries, physical therapies, and medicines that reduce risks and decrease recovery time.
- Targeted administration – Stem cells can be injected directly into the affected area for maximum and quick impacts.
- Long-term relief – Stem cell therapy provides long-term relief from pain and other sciatica symptoms compared to ongoing therapies, medicines, or surgeries.
Regenerative medicine such as stem cells is reshaping the future of pain management treatments. Quick recovery results, targeted pain management, non-invasive treatment methods, and reduced requirements for medications make stem cell therapy a popular option for patients suffering from chronic pain.
Conclusion
The Life Altering Stem Cell Therapy Institute is a renowned clinic equipped with the latest technologies to administer stem cell therapy.
We assess your overall condition and determine the extent of sciatic nerve pain. Our expert doctors prepare a personalized treatment plan based on the results.
Try this exclusive treatment and live a happy, healthy, and pain-free life.
How To Repair Torn Meniscus with Stem Cell Therapy
About 1 million US citizens experience meniscus tears every year.
Moreover, 9 out of every 1000 military personnel in the US go through meniscal tears during active service.
This type of knee injury is uncommon in children less than 10 years old.
Middle-aged people more than 40 years old and athletes have a higher risk of such injuries.
Surprisingly, medial meniscus tears are more prevalent than lateral tears.
People around the age of 20-29 years cover the highest percentage of meniscal tear injuries.
Let us find out how meniscus tears affect people and the role of stem cell therapy in healing this type of injury.
All About Meniscus Tears
We will identify the location of the meniscus. Also, we will discuss the causes of this type of injury. Furthermore, this section will explore the usefulness of conservative and surgical treatments to heal meniscal tears.
Understanding the Meniscus: Anatomy and Function
The meniscus is a C-shaped cartilage found in the knee joints. There are 2 meniscus in each knee.
There are three stages of meniscus tears. The first 2 grades are non-serious. However, an arthroscope test can detect the accuracy of a grade 3 meniscus tear.
The meniscus covers 70 percent of the articular surface of the tibial region.
This cartilage helps to load transmission and absorb shocks through the knee joints. The menisci improve the mechanism and movement of the knee joints.
The menisci has a composition of DNA, water, glycosaminoglycan, and collagen. It is a complex structure of different layers. Synovial fluid transports through microcanals within the meniscal tissue. It nourishes the articular cartilage.
The meniscus contains proprioceptive mechanical receptors that regulate the sensory functions of the knee joints.
Causes
Contact and non-contact injuries are the most common reasons for this type of knee damage. Moreover, degenerative diseases also increase the chances of this injury.
Surgery vs. Conservative Management for Meniscus Tears
The patient’s severity of the meniscal tear determines if they need conservative or surgical treatment.
Conservative management is appropriate for age-related tears.
Some conservative treatment techniques include ice, elevation, pain medicines, knee brace, and physical therapy.
Surgeries are essential for severe meniscal tears to improve knee function. Also, it helps to avoid long-term complications like osteoarthritis.
Surgical interventions are appropriate if conservative treatment does not help patients to return to daily activities.
Additionally, surgery options to completely or partially remove the menisci are also there. Patients can resume sports activities within 4-6 weeks of the surgery.
The meniscal tissue is hypocellular and avascular. This enables self-healing if damage occurs.
What Are Stem Cells?
Stem cells act as the repair system within the body. These are a set of cells that convert into different types of cells within the body. For example, stem cells transform into brain cells, joint tissues and cells, liver cells, insulin-producing cells, and cells in the lungs.
Different Types of Stem Cells
There is a dynamic range of stem cells found in the human body. The most prominent include –
- Mesenchymal Stem Cell (MSC) – Sourced from the bone marrow or human umbilical cord tissues (Wharton’s Jelly), these cells can differentiate and migrate. The multipotent cells are predominantly used for regenerative therapy.
- Embryonic Stem Cells (ESCs) – Extracted from the embryos, these stem cells can convert into any other type of cell in the body.
- Induced Pluripotent Stem Cells (iPSCs) – These are artificially modified cells created by transforming adult cells into embryonic stem cells.
Role of Stem Cells in Tissue Repair
Mesenchymal stem cells injected into the site of the meniscus tear release trophic factors that accelerate natural healing.
Furthermore, stem cells can be altered in a laboratory to convert into blood cells, heart cells, or nerve cells.
MSCs regulate the immune system responses to limit inflammation and protect tissues from degeneration.
Can Stem Cells Heal A Torn Meniscus?
Stem cell treatment for torn meniscus is a promising recovery option for patients with acute and severe meniscus tears.
It is a minimally invasive therapy compared to painful incisional surgeries.
Nevertheless, the patient should be eligible to receive the stem cell treatment for maximum effects.
Current Research on Stem Cell Therapy for Meniscus Tears
This section highlights the ongoing research and development in stem cell therapy for addressing meniscus tear issues.
Success Stories: Case Studies of Meniscus Repair with Stem Cells
Let us go through the results of some case studies. We will highlight the rate of improvement for meniscus repair with stem cells –
- Case 1 – An athlete had to go through stem cell treatment for the knee and experienced 35 percent improvement within 3 months of the therapy.
- Case 2 – 5 patients with degenerative conditions of the knee meniscus were treated with synovial MSCs at the site of the injury. MRI scans over 2 years highlighted no meniscal tear in the repair site.
The Benefits of Using Stem Cells for Meniscus Regeneration
There are multiple benefits of stem cell treatment for knee injuries. Let us dive into the benefits of meniscal repair –
- MSCs can transform into cartilage cells and fibrous material present in the meniscus that promotes regeneration.
- Stem cells relieve knee pain and promote meniscal tissue
- These cells can migrate to the site injury irrespective of the area of administration.
- MSCs release growth factors, cytokines, and chemokines.
Mechanism of Stem Cells in Meniscus Repair
Let us show you the mechanism of how this regenerative medicine helps repair a torn meniscus –
- Firstly, stem cells differentiate into the cells needed to repair the damaged meniscus. This includes chondrocytes and fibrous material.
- MSCs are easily available and possess chemotaxis. It regulates the immune system to prevent autoimmune reactions and infections.
- Stem cells release growth factors and cytokines to reduce the effects of inflammation on damaged meniscus cells and tissues.
How Stem Cells Promote Meniscus Tissue Healing
Let us find out the process by which stem cells promote meniscus tissue regeneration.
Tissue Regeneration Process using Stem Cells
Multipotent stem cells such as MSCs are more effective than pluripotent cells in promoting tissue repair. In this section, we will show you the process of tissue regeneration using stem cells –
- Firstly, stem cell activation helps to understand the micro surrounding of the infected, damaged, or injured area.
- MSCs instantly start multiplying when they come in contact with damaged tissues.
- The third step includes the transformation of stem cells into the required tissues.
- The final process is tissue regeneration where the stem cells are sequentially differentiated.
It is essential to note that several diseases and medicines can limit the effects of stem cells on tissue regeneration. These conditions include diabetes, obesity, steroids, chemotherapy, and alcohol abuse.
Growth Factors and Cellular Signals for Meniscus Repair
MSCS promotes meniscus tissue regeneration. Combining these stem cells with meniscus cells and growth factors promotes cell growth and tissue formation for meniscal tear patients.
- The meniscus tissue has a high supply of blood cells that promotes regeneration.
- MSCs stimulate beta 1 growth factor production.
- It promotes connective tissue regrowth with the help of MSC migration.
- Accelerates blood vessel formation and meniscal cell transformation.
- Multiplication of fibroblasts and transformation into myofibroblasts.
Current Stem Cell Treatment Options
Stem cells release proteins to stimulate self-multiplication of cells. Some of the modern healthcare approaches for treating meniscal tears using stem cells are –
- Meniscal mesenchymal stem cells have the properties to heal meniscus tears.
- Synovial MSCs found in the knee joint capsule to repair knee injuries.
- MSCs derived from bone marrow are directly injected into the injured joints.
Injection-Based Therapies Using Stem Cells
We will navigate the different methods by which stem cell injections are given to a patient.
Stem Cell-based Surgical Approaches
Several surgeries use novel stem cells to promote self-healing and reduce long-term complications. Surgeries using stem cells are used to treat autoimmune disorders, blood disorders, and orthopedic conditions. Some of the common surgeries using stem cells are –
- Stem cell transplants – A non-surgical method to inject stem cells derived from different sources to replace damaged tissues and cells.
- Intraoperative methods – MSCs are applied to a lesion directly, injected with a scaffold, or channeled through the veins for intravenous infusions.
- Allogeneic Simple Limbal Epithelial Transplantation – A surgical method to treat patients who have limbal stem cell deficiency.
Stem Cell Therapy vs. Traditional Surgeries: A Comparative Study
Both methods of treatment have their own benefits and drawbacks. Let us compare the effectiveness of each treatment –
Differences | Stem Cell Therapy | Surgeries |
Invasion | Minimal | Incisions or cutting of skin may be required
|
Scars from treatment | No scars | Possible scars from a surgical cut on the skin
|
Hospitalization requirements | No need to be hospitalized | Mandatory hospitalization |
Post-treatment medication | Not required | May be needed for up to a month after the surgery
|
Recovery Time | It can take up to 30 days for a full recovery. | Can take up to 2-3 months |
Post-Surgical Complications | Negligible | Moderate to High |
Insurance coverage | Therapy is not insured | Part or total expenses are covered by Medicare depending on the condition |
Read Also: How Does Stem Cell Therapy Help In Knee Cartilage Repair?
Impact of Stem Cell Therapy on Orthopedics
Mesenchymal stem cells can transform into mesodermal tissues. This helps to develop the tissues into bones, muscles, cartilage, tendons, and ligaments. Stem cell applications in orthopedics include –
- Heal bone defect traumas using scaffolds like hydroxyapatite and tri-calcium phosphate with stem cells.
- Stem cell spinal fusions for assisting peripheral nerve surgery.
- Reverse the symptoms and causes of intervertebral disc degeneration.
- Heal spinal cord and peripheral nerve injuries.
- Repair articular cartilage such as the meniscus.
- Stop the effects of osteoarthritis with matrix metalloproteinases infused with MSCs.
- MSCs have the potential to replace joint surgeries using three-dimensional scaffolds.
- MSC combination with bone morphogenic protein 2 promotes biomechanical properties of the tendon.
Ongoing Clinical Trials and Research
Here are some insights into the research and progress related to stem cell therapy.
Innovative Stem Cell Methods
The therapeutic effects of stem cells have gained high popularity for treating different diseases and injuries. Noteworthy applications of stem cells include –
- Biomaterials are prepared to deliver stem cell regulatory signals through a particular method.
- Nanotechnology helps in stem cell isolation, purification, and differentiation. This method is applied for treating neurological diseases.
- Intramyocardial injections are directly given to the applicable location with proper anesthesia.
Personalized Treatment for Meniscus Tears
Doctors can prepare a personalized plan of treatment for your condition. Stem cell therapy for torn meniscus highlights the following benefits –
- A minimally invasive procedure that can be completed in 1 day.
- Prevents the requirement for painful surgeries.
- Discards the recovery time and complications related to post-surgical methods.
- Stem cell therapy reduces the joint pain and symptoms associated with a meniscus tear.
- Helps to regenerate the damaged tissues in the knee joint.
Is Stem Cell Therapy The Right Option?
Stem cells are a promising option if you are looking for a non-surgical method to repair an injured meniscus.
However, there are several factors you should consider before determining if stem cell therapy is your ideal choice.
Moreover, your eligibility plays a crucial role in identifying if at all you can receive stem cell treatment.
For example, complete damage or depletion of the meniscus cartilage requires surgical interventions. Stem cannot regenerate the meniscus in extreme conditions of injury.
Surgeries increase the risk of infections and complications. It takes much longer to recover from surgery than stem cell therapy.
Furthermore, some diseases and injuries are beyond the reparative capabilities of stem cells. Therefore, surgical interventions or other treatments remain as alternative options.
The success rate of stem cell therapy and surgeries varies depending on the patient’s condition.
Read Also: Stem Cell Treatment or Knee Replacement Surgery: A Comprehensive Guide
Factors to Consider Before Opting for Stem Cell Treatment
This section will give you an idea of the different factors considered in stem cell therapy. Additionally, we will help you prepare the right set of questions to ask your consultant to prepare an accurate treatment plan.
Read Also: Stem Cell Therapy Benefits for Hip Bursitis Treatment
Considerations for Choosing Stem Cell Treatment
Talk to specialists from The Life Altering Stem Cell Therapy Institute in Mexico to determine the positive and risk factors of the treatment.
Consulting with stem cell experts gives you a better understanding of the different types of stem cells. You will get an idea about the costs related to medical tourism in Mexico.
They can explain the administration methods, number of sessions, and number of stem cell doses for the treatment.
Moreover, our clinical experts give you insights related to the different conditions that can be treated with stem cell therapy.
The vital details related to stem cell therapy help you make informed decisions.
We not only help diagnose the extent of your meniscus tear but also prepare a treatment plan to fully repair the injury.
Stem cell therapy improves mobility and reduces joint inflammation for meniscal tear patients. Also, it alleviates the injury pain.
You can get back to daily activities and sports with no risks or side effects after the treatment.
Stem Cell Therapy Benefits: A Revolutionary Cure for Hip Bursitis
Hip bursitis commonly affects women. A study was conducted on patients suffering from inflammatory disorders. The total number of patients was 877. 177 out of them were diagnosed with hip bursitis.
1.8 percent out of 1000 patients are affected by hip bursitis annually.
Bursitis impacts people from all age groups. However, the athletes experience the condition more than normal people. Nevertheless, middle-aged men are mostly affected.
Bursitis of the hip causes degradation of the bones, muscles, tendons, and ligaments. Conditions such as rheumatoid arthritis and diabetes aggravate the inflammation.
Sports injuries and infections increase the chances of hip bursitis.
Stem cells offer therapeutic treatment to relieve pain from bursitis.
This blog explores the potential of novel mesenchymal stem cells (MSCs). Also, we will check out how it helps to repair hip bursitis for patients of all age groups.
Overview of Hip Bursitis
Bursitis is a condition where the bursa is swollen due to inflammation. The bursa is a sac-like structure found in nearly 150 sites within the body.
These components enable the movement of the musculoskeletal system. It helps to create a cushion between the tissues and bones so that they do not collide against each other.
The friction of the bursa or inflammation causes bursitis. The condition is highly painful and limits your mobility. Connective tissues filled with synovial fluid compose the bursae.
Bacterial inflammation causes infections and fever. The presence of more fluid than usual in the bursa is called effusion. It leads to external swelling and internal inflammation.
The bursitis area can appear red and warm. It is easy to diagnose an inflamed bursae. They are painful and sensitive to pressure.
Diagnosis
Here are some common tests to detect bursitis of the hips –
- Physical exams such as standing on the affected leg to determine the tenderness of the hip.
- Imaging tests such as X-rays and MRIs to detect the cause of hip pain.
- An aspiration test where doctors apply a needle to remove the excess fluid from the bursa and check for infections.
- Blood tests may be necessary to detect additional complications.
Causes
The causes of hip bursitis are –
- Activity-related injury – Excessive running, cycling, or standing for prolonged periods can result in hip bursitis.
- Injuries – Accidents, falls, or other fatal blows irritate the bursa and cause bursitis.
- Arthropathic causes – Joint injuries due to rheumatoid arthritis, osteoarthritis, and lupus heighten the bursitis risks.
- Bone spurs – An extended bony structure near the joint end of the bone can develop bursitis. Moreover, calcium deposits to the bone also aggravate the condition.
- Post-surgical trauma – Fractures and hip replacement surgeries increase the risk the hip bursitis.
- Imbalanced muscles – Bodily imbalance stresses the hip muscles and causes bursitis.
- Obesity – Bursitis can develop if a patient is obese. Body balance and muscle strength are significantly affected.
- Spinal cord problems – Problems in the spine such as scoliosis enhance the scope of hip bursitis.
Symptoms
Hip bursitis symptoms are –
- Sharpened pain in the hip area that worsens while sitting or lying down. Patients with hip bursitis mostly experience pain on the outside of the hip and the side of the upper thighs.
- Repetitive motions increase the pain in hip bursitis patients. Climbing stairs, cycling, and heavy lifting are such motions.
- Inflammation causes swelling and redness in the affected region. Extra synovial fluid in the sacs aggravates the condition.
- Stiffness of the hip joints.
- Reduced mobility or immobility of the affected area. This restricts walking and other activities.
- A clicking or aching sensation on the side of the knee and at the side of the thigh.
NOTE: The symptoms of the disease vary depending on the severity of the condition. So, each hip bursitis patient will demonstrate different symptoms.
Complications
Some of the complications related to hip bursitis include –
- Chronic pain due to inflammation and swelling
- Reduced mobility of the joints leading to muscle loss in the affected area
- Thickening of the bursa due to swelling that limits mobility
- Calcium build-up in the soft tissues of the hip joint that can permanently impair movement
- Sleep disturbances for patients who sleep on their sides
- Limping due to an imbalance of the hip joints
- Snapping sounds of the hip tendon increase the pain
Who is at Risk?
The risk of hip bursitis is maximum for –
- Athletes with strained bursa
- Smokers who delay tissue healing
- Bedbound patients with restricted mobility and extra pressure on the same joints of the body
- Elderly and middle-aged people who had accidents and got badly hurt around the joints
- People with spinal cord problems
- Patients who had hip-related surgeries
- Overweight people who stress their hip joints
Read Also: How Stem Cell Therapy Can Treat Avascular Necrosis of the Hip
All About Stem Cells
MSCs are extracted from human umbilical cord tissues (Wharton’s Jelly). These cells are multipotent. HUCT-MSCs have several properties. Stem cells are anti-inflammatory and immunomodulatory. Furthermore, stem cells have differentiation and migration abilities. Most importantly, it enables self-renewal of damaged tissues and cells. Additionally, MSCs promote the production of cytokines and growth factors.
Regenerative properties and minimally invasive treatment methods make stem cells a popular healthcare choice. MSCs restore the pelvic joint’s self-healing abilities.
Stem cells transform into different cells of the body. Moreover, they migrate to different areas affected due to diseases or injuries. It promotes healing from several conditions. Various diseases affect different cells of the body. Consequently, the organ functions are limited.
There are different types of stem cells. However, MSCs are prevalently used for treatment due to various properties.
Administration Methods
The methods for administering stem cell therapy include –
- Intravenous (IV) – The MSCs are injected into the veins of the patients. It is given through infusions.
- Intraarticular (IA) – Injections are directly given into the affected joints of the bursitis patient.
- Intramuscular (IM) – An appropriate muscle is selected to inject the stem cells into the patient.
NOTE: The stem cell expert will determine the best administration method after evaluating your condition.
Cost of Stem Cell Therapy
Stem cell therapy costs vary depending on the type of disease or injury. Several factors contribute to the expenses for this holistic treatment. It is essential to understand that the cost of treatment is not the same for everyone.
Therapy using mesenchymal stem cells is life-changing and one of the most affordable treatment options in Mexico.
Let us check out the different factors that impact the treatment costs –
- The age of the patient
- Type of the disease and severity of the condition
- Extent of hip pain
- Pre-existing medical conditions such as diabetes, rheumatoid arthritis, lupus, osteoarthritis
- Previous surgical records such as hip replacement
- Changes in medical settings
- Source of mesenchymal stem cells
- Volume of MSCs
- Number of stem cell therapy sessions
- Unidentified costs
Eligibility for Administration
Candidates are carefully evaluated to determine their eligibility for stem cell therapy. Here are the criteria to determine the eligibility of a patient –
- Patient’s age, gender, weight, and height
- Existing diseases such as gastrointestinal issues, cardiovascular issues, autoimmune conditions, and neurological diseases
- History of previous surgeries
- Lifestyle and habits
Stem cell doctors will create a plan of treatment based on the factors related to the patient.
Impact of Stem Cells on Hip Joint Pain Relief
Stem cell treatment is a non-surgical process for hip bursitis. 80 percent patients of with this condition who chose stem cell therapy highlighted significant pain relief. Additionally, the therapy helps to restore the mobility of patients.
MSCs regulate the immune responses to reduce the inflammation of the bursae. Stem cells offer a non-surgical treatment for hip pain from bursitis.
Moreover, stem cells are an alternative treatment to painful surgeries for hip bursitis. Also, it eliminates the requirement for corticosteroid injections. This discards the need for anesthesia.
The stem cells can regenerate the damaged tissues in the affected region. Moreover, reduced inflammation helps to deject the extra synovial fluid from the bursae. This significantly reduces the pressure sensitivity.
The effects of the treatment are experienced within a few weeks while the symptoms of the disease are considerably reduced.
Additionally, the downtime for stem cell therapy is extremely low. It allows patients to get back to normal life within a week. Moreover, no hospitalization is required for getting this treatment.
Stem cells improve muscle flexibility and ligaments of the hips.
Patients regain mobility and experience long-term pain relief from the condition.
MSCs dissolve the root causes of hip bursitis.
Benefits of Stem Cell Injections for Hip Bursitis
Here are the benefits of treating hip bursitis with stem cells –
- A regenerative medicine that activates T-cells to secrete chemokines and cytokines for hip bursitis treatment
- Accelerates cell differentiation and produces new tissues and cells
- Regeneration of blood vessels
- Circulation of cells through the blood vessels in the hip
- Regulates the immune system responses to prevent infections
- Stem cells provide relief from hip joint pain and reduce bursa inflammation
- Improves the mobility of the patient
- Stem cell therapy for hip inflammation is treated within 1-5 sessions
- Patients highlight improvement in conditions within 7-30 days of the treatment
- The side effects of stem cell therapy are negligible and it is safe to get more than one injection
- It is a non-surgical method that reduces the risks related to post-surgical complications
Read Also: Stem Cell Therapy for Autoimmune Hepatitis
Bottomline
Hip bursitis impacts the quality of life. It affects the way you move and the way you sleep. Several complications can arise if you have additional diseases.
Ignoring the symptoms and causes of the disease increases the chances of invasive surgeries.
The Life Altering Stem Cell Therapy Institute in Mexico is renowned for its holistic treatment methods. We are an American-owned clinic.
We have state-of-the-art equipment and certified stem cell experts to curate an effective treatment plan for you.
Alleviate the symptoms of the disease, move freely, and engage in your favorite sports. The functions in the hip region are considerably improved.
The scientific advancements in the healthcare industry have introduced the holistic treatment option. Experience natural healing with our stem cell intervention.
Stem Cell Therapy for Autoimmune Hepatitis: A Revolutionary Cure
Nearly 10 out of 100,000 children are at risk of developing autoimmune hepatitis (AIH). The disease affects the liver’s functions and decreases the patient’s lifespan considerably.
The number of patients suffering from autoimmune diseases is undetected. However, an estimation is made that nearly 200,000 Americans are annually affected by this condition.
The mortality rate for autoimmune hepatitis is high and 50 percent of patients with severe AIH can pass away between 6 months to 5 years after developing the disease.
AIH affects more females than males. Furthermore, up to 45 out of 100,000 adults can also develop autoimmune hepatitis.
The liver of the patient is severely affected by this type of disease.
Nevertheless, novel stem cell therapy brings hope for curing autoimmune hepatitis. Children and adults can be effectively treated with this holistic therapy.
In this blog, we will explore the risks related to AIH and the potential benefits of mesenchymal stem cells (MSCs) in healing patients from the deadly effects of the disease.
What are Autoimmune Diseases?
Autoimmune diseases occur when the body’s immune system attacks healthy cells and organs. More than 100 types of autoimmune diseases exist. Such diseases can harm any part of the body.
Skin problems, joint pain, fever, and abdominal problems are some of the common symptoms of varied autoimmune disorders. The failing immune system loses its ability to protect the body against internal and external dangers such as viruses or inflammation. Naturally, the body becomes weak and susceptible to several diseases.
A person with a family history of such diseases is prone to developing a similar condition. Furthermore, the age group of 15-44-year-old females has a higher risk of suffering from autoimmune disorders. Obesity, smoking, and environmental factors such as exposure to toxins and chemicals increase the possibility of these diseases.
Types of Autoimmune Diseases
Common autoimmune diseases are –
- Psoriasis – Dead cells are accumulated on the epidermal layer of the skin. It forms scaly and red patches on the site of the disease. This is a skin problem that causes rashes and itchiness. Additionally, it can trigger anxiety and impact the confidence of the individual.
- Lupus – A type of disease in which the immune system of the body attacks the healthy tissues. It can affect the heart, lungs, joints, brain, kidneys, and skin.
- Rheumatoid Arthritis – A chronic joint inflammation disorder leading to pain, swelling, and stiffness of the joints. The disease can destroy the healthy joint tissues and cells.
- Crohn’s Disease – A bowel disorder that affects the digestive tract of the patient and limits their digestive abilities. Inflammation in the gastrointestinal tract is the primary reason for this type of disease.
- Multiple Sclerosis – The myelin sheath covering the central nervous system is depleted due to the activities of the immune system. The nerve endings are left uncovered in this disease leading to a wide range of disabilities.
Overview of Autoimmune Hepatitis
Autoimmune hepatitis is an immunity-related disease that damages the liver. The immune system starts to attack the liver and causes tissue scarring, pain, and swelling. The functions of the organ are completely destroyed.
Untreated autoimmune hepatitis can lead to liver cirrhosis. The function of the immune system is to protect the body from infiltrating bacterial or viral infections. However, in this type of disease, the immune system severely damages the liver cells.
The levels of aspartate aminotransferase, alanine aminotransferase, immunoglobulins, anti-liver kidney microsomal type 1, and smooth muscle antibodies are detected in the serum of autoimmune hepatitis patients.
Cytotoxic T cells are autoantibodies that enhance the hepatic damage to autoimmune hepatitis patients. A liver transplant may be the only treatment option in this last stage of the disease.
Types of Autoimmune Hepatitis
There are 2 notable types of autoimmune hepatitis. These are –
- Type 1 – This disease affects anybody regardless of their age. It is caused due to the presence of anti-smooth muscle antibodies (ASMA) in the blood. Pain in the belly, jaundice, and loss of appetite are symptoms of type 1 autoimmune hepatitis. Most people suffering from this disease are also affected by other types of autoimmune disorders such as rheumatoid arthritis and ulcerative colitis.
- Type 2 – This is a rare form of AIH that mostly affects children due to the presence of hepatitis B, C, or D virus. Accumulation of fluid in the belly, dark urine, and rectal bleeding are common symptoms of type 2 autoimmune hepatitis.
Females, people with a genetic history of hepatitis, and patients with other types of autoimmune diseases have higher risks of developing autoimmune hepatitis.
Diagnosis
A single test is not enough to confirm the presence of autoimmune hepatitis. More than 1 blood tests and imaging tests are essential to detect AIH. Diagnosis methods include –
- Liver Biopsy – A tissue from the liver is extracted through medical equipment to detect the signs of autoimmune hepatitis.
- Blood Tests – Serum bilirubin and albumin are essential liver function tests to detect and confirm AIH.
- Imaging Tests – Tests such as ultrasound, MRIs, and CT scans help detect enlarged perihepatic lymph nodes which is one of the symptoms of autoimmune hepatitis.
- Endoscopy – A medical device is inserted within the body to check for swollen veins in the stomach or food pipe to confirm the presence of AIH.
Causes
The liver and immune system’s inability to perform its natural functions leads to AIH. However, broader causes of the disease include –
- Genetical factors – Genetic components such as non-HLA epitopes, vitamin D receptors, and CTLA-4 contribute to the development of AIH. If there is a family history of autoimmune hepatitis, patients are more likely to develop such a condition over their lifetime.
- External factors – Viruses and environmental factors such as pollutants, chemicals, and toxins can inhibit the function of the liver and damage the tissues and cells.
- Failure of the immune system – A patient’s immune system fails to protect the liver from infections and diseases and attacks the liver cells instead. The liver is significantly damaged.
- Autoimmune disorders – Hyperthyroidism, ulcerative colitis, and type 1 diabetes are some autoimmune diseases that increase the risk of autoimmune hepatitis.
- Hypergammaglobulinemia – The presence of excessive protein antibodies in the blood causes chronic infections that promote this rare type of blood disorder.
Symptoms
Some people exhibit few symptoms while other patients can highlight a variety of symptoms. However, here are some of the factors to determine if the patient is affected by type 1 or 2 autoimmune hepatitis –
- Discomfort in the belly
- Fatigue and energy loss
- Liver and spleen enlargement
- Pain in the joints
- Missed out menstrual cycles in females
- Disformed blood vessels
- Itchy feeling on the skin
- Nauseating feeling
- Digestion and bowel problems
- Fever
These symptoms may not be evident enough to confirm the presence of autoimmune hepatitis. Therefore, additional blood or imaging tests are necessary to detect AIH.
Complications
Autoimmune hepatitis can lead to liver cirrhosis that causes scarring of the liver tissues. Additional complications due to this disease are –
- The veins in the esophagus are enlarged. Due to this, the blood circulation to the liver is disrupted. Sometimes, the blood enters smaller veins that can rupture easily when they cannot take the pressure. This causes internal bleeding.
- Accumulation of ascites, a distinct fluid in the abdomen that hinders the normal breathing abilities of a person.
- Damaged liver tissues and cells lead to failure of the liver. A transplant surgery may be necessary in such an instance.
- Patients who have liver cirrhosis and autoimmune hepatitis are prone to developing life-threatening prostate cancer.
Read Also: Stem Cell Treatment for Philadelphia, Pennsylvania Patients
Role of Stem Cells in Autoimmune Hepatitis Treatment
Multipotent MSCs are derived from human umbilical cord tissues (Wharton’s Jelly). Mesenchymal stem cells can multiply into osteoblasts, chondrocytes, and adipocytes. The self-healing properties of MSCs regulate the behavior of the different immune cells. In this instance, it is used to reverse the effects of the immune system on the liver.
The inhibition of lymphocytes and its effects is an MSC feature that prevents the onset of liver damage. It helps to improve the tolerance of the immune system.
Additionally, these cells promote the proliferation of tolerogenic T regulatory cells. The T cells are essential to improve the self-tolerance of the peripherals.
MSCs activate the immunosuppressive activities in the inflamed cells and tissues. The ability of mesenchymal stem cells to communicate with macrophages, natural killer cells, neutrophils, dendritic cells, and mast cells promotes the immune system’s tolerance. Stem cell therapy can prevent autoimmune diseases in the future.
Tissue regeneration is an invaluable property of MSCs that makes it a popular treatment choice for patients.
Research on stem cell therapy for autoimmune hepatitis highlights therapeutic effects.
Furthermore, stem cell treatment for autoimmune hepatitis is a minimally invasive method compared to liver transplant surgeries. Patients are injected doses of stem cells in an intravenous (IV), intra-articular, and intramuscular methods.
MSCs can not only transform into other types of cells and tissues but also migrate to different areas of the body regardless of the administration site.
Benefits of Using Stem Cells to Cure Autoimmune Hepatitis
Here are some attractive results of stem cell therapy for autoimmune hepatitis patients –
- Reduces the rate of mortality
- Improves the functions of the liver
- Reforms liver tissues and cells
- Prevents the escalation of the disease that could lead to cirrhosis or cancer
- Prevents the immune system from attacking the liver
- Stops hepatocyte apoptosis
- Regulates the level of antioxidants
- Adopts anti-inflammatory phenotypes
The stage of the disease determines the treatment benefits. At an early stage, stem cell therapy is highly beneficial in stopping, reversing, and preventing autoimmune hepatitis from transforming into a more serious disease.
Read Also: Stem Cell Therapy vs. Surgery: How To Pick The Right Treatment?
Takeaway
If you are looking for a holistic and minimally invasive treatment that offers a long-term cure, stem cell therapy is the appropriate option.
The Life Altering Stem Cell Therapy Institute in Mexico is a renowned clinic treating more than 20 conditions with MSCs.
A happy and healthy liver automatically improves the health condition of a patient. Do not let autoimmune hepatitis cause further complications in your life. Talk to our experts and address the diseases before they become life-threatening.