How To Treat Premature Ovarian Failure with Mesenchymal Stem Cell Therapy?

What is the Conditional Diagnosis?

Healthcare providers can diagnose POF by applying the following techniques –

• Pregnancy Test – A pregnancy test to determine if the candidate is eligible to conceive and deliver babies. Also, to determine if the women missed their menstrual cycle or got irregular periods.
• Physical Exam – Physical tests are conducted to check signs of disorders or diseases that could be present in the female. Addison’s disease is one such example that can be detected with the help of this test.
• Blood Samples – Blood samples are collected to test for follicle-stimulating hormone, estrogen levels, luteinizing hormone levels, and karyotype tests.
• Pelvic Ultrasound – A pelvic sonogram test gives an internal view of the woman’s ovaries highlighting unnatural ovary growth or multiple follicles.

Signs and Causes of Premature Ovarian Failure

Multiple symptoms indicate premature ovarian failure in women. The inability to conceive and early menopause are the leading signs. However, let us walk you through the details of the symptoms –

Symptoms

Noteworthy symptoms of POF –

• Irregular or missed menstrual cycle for 4 months at a stretch
• Lowered levels of estrogen
• Enhanced follicle-stimulating hormone levels
• Trouble and incapability towards pregnancy
• Reduced sexual drive
• Mood fluctuations assisted with
• Disturbed memory and concentration
• Night sweats
• Neurological disorders such as disputed cognitive abilities, Parkinson’s disease, dementia, and speech loss
• Estrogen deficiency weakens bone health density

[Read Also: Transform Your Health with Stem Cell Therapy in Miami ]

Causes

Top causes of POF –

• Changes in the Chromosome – Chromosomes contain genes that distinguish the gender of a person at birth. Females have two X chromosomes. However, women with insufficient X chromosomes have one altered type of X chromosome that can be fragile. This condition is fragile X syndrome.
• Exposure to Toxins – Radiation-based therapies used to treat patients with cancer can induce toxins into the ovary causing insufficiency. Genetic materials in the cells are destroyed due to these strong treatment techniques. Environmental toxins such as chemicals, cigarette smoke, and viruses can lead to POF.
• Response of the Immune System to Ovarian Tissue – The immune system develops protective proteins that attack the ovary tissue mistakenly. Ovary follicles or eggs are damaged.
• Unprecedented Factors – Idiopathic diseases that affect a female without any proper source or cause can enhance premature ovarian failure.
• Lifestyle – Several lifestyle factors such as poor nutritional intake, lack of sleep, excessive use of tobacco, and lack of physical activities can aggravate the condition.

What is the Equivalent Medical Condition for Males?

Infertility issues are not only limited to women but also affect a large number of the male population. Erectile dysfunction is the leading infertility issue in men. It can affect any man regardless of their age. Long-term persistence of this condition can lead to impotence. It physically limits a man’s ability to have sex organ erections.

Erectile dysfunction can lead to a wide range of heart and health diseases such as diabetes. Other than this, leading causes of ED include hypertension, low testosterone levels, obesity, cardiovascular diseases, and psychological causes such as stress and depression.

Nevertheless, advanced erectile dysfunction treatments with stem cell therapy provide relief and boost confidence in men significantly.

Here are the benefits of choosing stem cell therapy for POF –

• Improved tissue and cell regeneration for enhanced blood flow
• Improves the sensitivity of the sexual organ to enhance performance
• A minimally invasive and painless administration technique with fast recovery results
• Best-quality human umbilical cord mesenchymal stem cells are administered to ensure zero rejection chances

Importance of Mesenchymal Stem Cells for Premature Ovarian Failure Treatment

Stem cells can reverse the limited functionalities of the ovarian endocrine system and restore fertility in women.

Mesenchymal stem cells have several therapeutic effects. It can improve the overall functioning of the ovaries and reduce the signs and causes of GC apoptosis. Moreover, mesenchymal stem cell therapy can boost the following for women with premature ovarian failure –

1. Improves folliculogenesis
2. Enhances the rate of GC apoptosis
3. Accelerates vascular formation
4. Regulates the level of hormones
5. Improves the chances of pregnancy
6. Restores the menstrual abilities
7. Decreases FSH levels
8. Increases AMH levels
9. Improves ovarian weight
10. Ability to differentiate egg cells
11. Enhance the production of estrogen and progesterone

Results of Stem Cell Therapy

Before we explore the results related to stem cell therapy for premature ovarian failure, let us navigate the administration techniques for stem cells.

Administration Technique

The stem cells are administered applying intravenous (IV) techniques where an injection is introduced in the ovary region. The process takes 4-5 days to complete. However, different administration techniques are followed for different patients depending on their age, weight, and condition.

Treatment Results

POF Treatment results with stem cells include –

• Improved fertility – Ability to get pregnant and healthy formation of eggs.
• Enhanced sexual drive – Increased hormonal activities leading to natural sexual capabilities.
• Regeneration of healthy hormones – Repair, replacement, and regeneration of healthy estrogen.
• Repaired ovarian tissues – Repaired ovarian follicles and tissues for better functioning.
• Prevention of infertility causes in the future – Prevents the recurrence of POF in women in the future and ensures a healthy ovarian system.