What Is Brain Damage?

Brain damage is a dangerous type of injury that impacts the functioning of the brain and can lead to temporary or permanent disability. A traumatic brain injury typically results from sudden external and impactful force to the head that damages the brain tissues. The consequence of the injury may range from severe disabilities to mild concussions or even death, depending on the intensity of the external force.

Non-traumatic brain damage is a condition that occurs when any internal health factors, such as stroke, disease, or aneurysms, disrupt the flow of blood to the brain, impacting brain function. In some brain injuries, the effect or damage is felt immediately, while in some cases, patients experience outcomes after days or weeks.

Symptoms Of Brain Injuries

The symptoms of brain injuries depend on the degree or intensity of injury in the brain. When the extent of the damage ranges from mild to moderate, patients can experience loss of memory, communication, and understanding problems. Also, the symptoms may vary from person to person and may include:

• Headaches
• Bleeding from the nose or ears
• Trouble Sleeping
• Numbness or weakness in the body
• Vomiting
• Convulsions
• Slurred Speech
• Unusual Behavior
• Dizziness
• Blurred vision

Primary Causes Of Brain Injuries

Brain damage can happen for lots of reasons like accidental falls, infections, tumors, or neurodegenerative diseases, impacting specific parts or regions in the brain and leading to cognitive disability. Here are a few risk factors that contribute to brain damage –

• Traumatic injury – Sudden jolt or blow to the head with extreme force during sports, car accidents, falling from heights, etc.
• Stroke – Ischemic stroke or hemorrhagic stroke that blocks the supply of blood to the brain. Lack of oxygen and nutrients stops the brain from functioning correctly.
• Neurodegenerative diseases – Brain disorders, such as Alzheimer’s Disease or amyotrophic lateral sclerosis (ALS), progressively damage brain tissues and lead to cognitive decline.
• Brain Tumors – Abnormal cell growth within the brain leads to the formation of tumors that exert pressure on nearby cells and impact brain function.

Can Stem Cell Therapy Help Treat Brain Damage?

Stem cell therapy holds tremendous potential in recovering the damage caused to the brain due to various external or internal factors. The distinct properties of stem cells aid in tissue repair and regeneration, improving a patient’s condition and quality of life. The therapeutic benefits that stem cells offer in treating brain injury are –

• Regenerative Potential—Stem cells can differentiate into various cell types, including brain cells, facilitating healthy tissue regeneration in damaged regions.
• Neuroprotection – Stem cells release growth factors and other neuroprotective agents that regulate inflammation and promote neural cell survival.
• Promote Neurogenesis – Stem cells support neuronal growth and differentiation, replacing damaged neurons and improving brain function.
• Promote Angiogenesis – Stem cells also result in the growth of new cerebral blood vessels, which enhance the supply of oxygen and nutrients to the brain.

To sum up, stem cell treatment for brain injury helps restore lost neural cells through proliferation and cell differentiation. These cells transform into brain and nerve tissues, such as oligodendrocytes, endothelial cells, and astrocytes, to restore cognitive and motor function.

Recent Studies Showing Positive Outcomes In Brain Injury Patients

Numerous animal studies have established preclinical success for stem cell therapy, demonstrating its therapeutic benefits in treating brain injury. Other ongoing studies and clinical trials in human subjects show stem cells’ promising efficacy in significantly improving patients’ conditions.

A study on 46 brain injury patients indicated impressive results from a more practical perspective. There was an improvement in their balance skills, better posture, and increased motor skills. Patients could move their arms and legs and even walk again, which reduced their dependence on a wheelchair.

Where To Get the Best Stem Cell Therapy In Mexico

Life Altering Stem Cell Therapy Institute is Mexico’s best place for stem cell therapy. It is known for its highly advanced treatment facility, experienced team of medical professionals, and cutting-edge technologies. Our treatment center is located in Mazatlan, Sinaloa, and is easily accessible from the famous cities of the US and Canada, making it a preferred destination for medical tourism.

After reviewing the patient application form, we provide personalized treatment solutions for over twenty medical conditions. We approve treatment only after careful evaluation of the patient’s age, current condition, the severity of the disease, and medical history to ensure safety and maximum effectiveness.

Fanconi Anemia and Its Symptoms

The center of the bone marrow in the human body contains spongy tissues that produce hematopoietic (blood) cells, including red blood cells, white blood cells, and platelets. Fanconi Anemia is a genetic disease characterized by bone marrow failure, resulting in lower blood cell production. FA patients have physical deformities that impact their appearance and organ function. This inherited condition is passed down through families, and symptoms generally start appearing at birth or in the early childhood phase between 5 and 10 years.

The most common symptoms of FA are:

• Fatigue or extreme tiredness – Patients may find difficulty carrying out essential daily tasks.
• Pale skin color
• Headaches
• Frequent infections due to low white blood cell count
• Nose or gum bleeding
• Abnormal function of the heart, lungs, and digestive tract
• Easy bruising

What Causes Fanconi Anemia?

Fanconi Anemia is inherited by receiving one copy of an abnormal FA gene from each parent. The FA genes repair damaged DNA throughout life and help the body function properly. Abnormal genes cannot protect against DNA damage and don’t repair routine DNA, leading to uncontrolled cell growth or death.

Abnormal cell death results in physical deformities in patients due to reduced amounts of hematopoietic (blood) cells. Whereas abnormal cell growth increases the risk of hematological malignancies, such as acute myeloid leukemia and other blood-related cancers.

The goal of Stem Cell Therapy For FA Treatment

Traditional and short-term treatments for FA involve using medicines to treat the symptoms without addressing the cause. These medications typically provide short-term relief by allowing the bone marrow to produce more blood cells for a limited time.

Stem cell therapy aims to provide lasting results by targeting the root cause of anemia. The long-term goal of hematopoietic stem cell transplantation is to replace the damaged bone marrow cells with healthy cells that will produce the required amount of all types of blood cells (mainly red blood cells, white blood cells, and platelets) on their own.

The doctors evaluate the patient’s age and physical condition to approve the therapy. After the transplant, the patient’s body must make enough new blood cells.

Stem cell therapy starts with stem cell harvesting, in which healthy stem cells from a donor’s bone marrow are collected and implanted in the patient’s body. Doctors try to find a donor whose stem cells match as closely as possible with the patient. HLA-matched (Human Leukocyte Antigen) related family donors, such as siblings, show maximum success, while unrelated donors can result in poor patient outcomes.

After collection, the stem cells are concentrated with solutions to prepare injections for the treatments. The stem cells are administered to the patient intravenously. Once the new cells enter the bloodstream, they travel throughout to reach the bone marrow to start healing and make new blood cells.

Clinical trials indicate the chances of success for hematopoietic stem cell transplantation are higher in younger people who have less or no severe existing health issues and have received fewer blood transfusions in the past. Also, those who receive stem cells from their brother or sister have shown better clinical outcomes.

Results of Hematopoietic Stem Cell Therapy For Fanconi Anemia

Doctors of reputed institutions studied patients, particularly children, who underwent stem cell therapy for Fanconi Anemia from 2000 to 2018. Normal hematopoiesis was restored in most patients, gradually increasing blood cell production. The red and white blood cell count and platelet count improved significantly.

As a result of increased levels of three types of blood cell counts, patients started experiencing improvement in their health condition in the following ways.

• An increase in energy levels with no more fatigue
• Lower infections and better capabilities to fight diseases
• Improved function of the heart, lungs, and digestive system
• Enhanced physical appearance
• Increased strength in the bones

Read Also: Healing Power Of Stem Cell Therapy: A Comprehensive Guide

What Is A Stroke And What Are Its Types?

A stroke is a severe health condition that occurs when the blood flow to the brain is blocked or interrupted for any reason, resulting in a lack of oxygen supply to brain cells and, ultimately, brain cell death. Body movements, perception, and speech ability are impaired, and patients may lose consciousness when a stroke happens. After cancer and cardiac failure, stroke is the third leading cause of death worldwide.

There are three major types of strokes depending on their causes or origin.

• • Ischemic Stroke – It is the most common type of brain stroke, comprising almost 87% of all stroke victims. The arteries carrying oxygenated blood to the brain are blocked by blood clots, causing an ischemic stroke. Consequently, there is a lack of oxygen supply to the brain cells, and patients experience sudden loss of movement, speech, vision, and balance.
  • Hemorrhagic Stroke – This type of stroke occurs due to bleeding in the brain when an artery gets damaged and breaks up, leaking blood into the brain. The damaged artery exerts enormous pressure on the brain cells, resulting in cell death. High blood pressure and Aneurysms are two primary reasons for hemorrhagic stroke.
  • Transient Ischemic Attack (TIA) – It is a “mini-stroke” that occurs from a temporary blockage of blood flow and oxygen supply to the brain cells. TIA typically lasts five minutes and is caused by blood clots in the arteries.

Related Read: Stem Cell Therapy: Ischemic Stroke Recovery Breakthrough

Effects Of Stroke – What To Expect After Having A Stroke

The effects of stroke depend on the area in the brain where the brain cell death has occurred and the number of cells damaged or dead. Also, the patient’s age, medical history, current condition, and type of medical attention provided at the time of stroke play a big part in determining the long-term effects of the stroke and the patient’s outcome.

The common disabilities seen in patients after having a stroke are –

• • Partial or complete paralysis
  • Weakness in one side or complete body
  • Limited ability to make movements
  • Memory loss
  • Speech impairment or changes in facial expression
  • Loss of control over bladder and bowel movements
  • Inability to eat or swallow

Early medical intervention is necessary for preventing these long-term disabilities, as mentioned above, and may lead to quick recovery, regaining some abilities that were lost.

Risk Factors For Stroke

The two most common and significant reasons for stroke are high blood pressure and smoking. Other risk factors that are responsible for stroke include:

• • Atrial Fibriallation (A-fib)
  • Heart failure or heart attack
  • History of Transient Ischemic Attack (TIA)
  • Birth control pills
  • High blood cholesterol
  • High levels of lipids or hyperlipidemia
  • Excessive alcohol intake
  • Obesity
  • Pre-existing heart diseases
  • Sickle cell disease

How Does Stem Cell Therapy Help In Stroke Recovery?

Stem cells have the distinct property to differentiate into various cell types, including neurons or nerve cells. These powerful cells help repair the damaged brain cells after a stroke and promote functional brain recovery. Stem cell therapy holds immense potential to regenerate damaged neurons and reduce the extent of damage in the affected parts of the brain.

Stem cells help in reversing the damage in the brain cells in the following ways:

• • They release growth factors and cytokines which help in the growth of new blood vessels from existing vessels through a process called angiogenesis.
  • Stem cells possess anti-inflammatory agents that help reduce neuroinflammation and repair damaged neural cells and tissues.
  • Stem cells regenerate damaged cells and help regain motor function in patients.
  • When they reach the injury site, stem cells activate their healing mechanisms and create a conducive microenvironment, facilitating functional recovery.
  • Besides promoting the growth of new and healthy cells, stem cells prevent further death of brain cells.

Types of Stem Cells Used in Stroke Recovery Treatment

Stem cell therapy for post-stroke recovery is a revolutionary treatment that reduces the adverse impacts of stroke and helps patients recover faster, thus leading a healthy life. Although several types of stem cells have shown the potential to promote the brain’s functional recovery after a stroke, mesenchymal stem cells have gained the most attention regarding their therapeutic benefits.

Mesenchymal stem cells are immature adult cells found in various tissues and organs of the human body. They are classified as pluripotent cells depending on their differentiation and regenerative characteristics. The three types of mesenchymal stem cells that make ideal candidates for stem cell therapy to regenerate damaged neurons are:

• • Bone marrow tissue
  • Adipose or fat tissue
  • Human Umbilical cord tissue

Benefits of Stem Cell Therapy For Stroke Survivors

Stem cell therapy offers numerous advantages that other alternative treatments or medications fail to provide. Emergency medical intervention is necessary to restore the flow of oxygenated blood to the brain, such as endovascular procedures or intravenous medications. However, these treatments save lives at the moment of the stroke, and the chances of recurrence remain, which necessitates the need for post-stroke recovery treatment like stem cell therapy.

• • Stem cell therapy is a minimally invasive and quick procedure requiring only one or two hours to complete.
  • There is no lengthy rehabilitation period; patients can return to routine within one to two days.
  • Stem cells promote functional recovery of the damaged region in the brain by activating the body’s healing response and stimulating cell repair.
  • Mesenchymal stem cells derived from umbilical cord tissue are easy to procure.
  • Umbilical cord tissue-derived stem cells are hypoimmunogenic and have zero risks of cell rejection because they can evade the host’s immune system.
  • Stem cell therapy is safe and effective with no adverse or long-term side effects.

Read Also: Healing Power Of Stem Cell Therapy: A Comprehensive Guide

What To Expect After Receiving Stem Cells

Patients are expected to notice the following significant and sustained improvements in their neurological function and overall health after a few weeks of receiving stem cells.

• • Increase in physical mobility or body movements
  • Better body balance and coordination
  • Increase in strength and energy levels
  • Better control over bladder and bowel movements
  • Improved speech
  • Increased ability to eat and swallow independently
  • Improved memory and concentration

It is essential to understand that every human body is different, so results may vary. Moreover, the location of the brain damage, the severity of the injury or brain lesion, and the timing of the stroke onset determine the effectiveness or impact of stem cell therapy.

Cost of Stem Cell Treatment For Post-stroke Recovery

The cost of stem cell treatment for post-stroke recovery might be higher than traditional treatment alternatives, such as physical therapy, occupational therapy, speech therapy, and medications. However, there is no denying that the outcomes of mesenchymal stem cell therapy are sustainable or long-lasting, unlike the other treatments. It helps enhance patients’ overall quality of life.

The factors that influence the cost of stem cell therapy are:

• • The source or types of stem cells used.
  • The method of stem cell extraction.
  • The clinic’s location.
  • The number of stem cell doses.

Stem cell therapy in Mexico is comparatively cheaper than in other countries, and it is currently the top preferred place for stroke patients worldwide. Life Altering Stem Cell Therapy Institute is a top-rated clinic offering advanced, high-quality stem cell treatment for stroke recovery.

What is Peripheral Neuropathy?

Peripheral neuropathy, or simply neuropathy, is dysfunctional or damaged nerves in the peripheral nervous system comprising the brain and the spinal cord. The nerve damage causes pain, swelling, numbness, and weakness in the muscles and different body parts. The symptoms of peripheral neuropathy depend on the affected nerves and can include:

• Abnormal tingling sensation in hands and feet
•  Limited muscle movements and function
•  Difficulty walking and balancing
•  Loss of muscle and bone
• Changes in the texture of skin, hair, and nails
•  Paralysis
• Foot ulcers

The symptoms of neuropathy usually begin in the hands or the feet and then gradually start affecting other body parts. If left untreated, it can get worse with intense pain followed by complete numbness or loss of sensation.

Causes and Types of Neuropathy

There are more than hundreds of types of neuropathy conditions, each depending on its cause and having its own set of symptoms. The most common cause of this severe condition is diabetes, and hence, it is also termed diabetic neuropathy. Its symptoms may range from mild to severe based on the areas in the body whose nerves are damaged. Diabetic neuropathy may cause nerve damage throughout the body due to consistently high glucose levels (sugar) in the bloodstream.

However, in several cases, chemotherapy, genetic factors, inflammation or infections, poor nutrition, and kidney failures have been the triggers for peripheral neuropathy leading to health deterioration. As per the latest reports of The National Institute of Diabetes and Digestive and Kidney Disease, almost 60-70% of the Type 1 and Type 2 diabetes patients suffer from diabetic neuropathy.

Other risk factors that contribute to neuropathy are excessive alcohol intake, bone marrow disorders, autoimmune diseases, liver problems, hypothyroidism, and vitamin deficiency.

The five types of neuropathy based on the types of nerve damage are –

• Peripheral neuropathy – Nerve damage in the brain and spinal cord
• Cranial neuropathy – Nerves in the brainstem are affected, resulting in damage to the optic nerve or nerve in the ear or face.
• Autonomic neuropathy – Nerve damage in the internal organs, such as the digestive, reproductive, or urinary systems.
• Focal neuropathy – Damage to a single nerve, such as hand, leg, head, or torso.
• Proximal neuropathy – It is a rare type of nerve damage that affects the lower portion of the body, such as the hips, thighs, and legs.

Why Choose Stem Cell Therapy for Peripheral and Diabetic Neuropathy?

Stem cell therapy is now at the forefront of advanced regenerative medicine treatment for neuropathy characterized by peripheral nerve damage. Mesenchymal stem cells collected from umbilical cord tissue (Wharton’s Jelly) are injected into the bloodstream via intravenous infusion to release neuroprotective agents to recover from the nerve damage. Stem cells have the exceptional power to regenerate nerve cells, potentially rebuilding the damaged nerves and restoring their functions.

Stem cell therapy for peripheral and diabetic neuropathy offers a glimmer of hope to patients, not just with symptom relief but promoting nerve repair and regeneration. It addresses the underlying cause of neuropathy and significantly alleviates the symptoms of motor neuropathy, such as a reduction in pain, weakness, and numbness.

Nerve regeneration using umbilical cord tissue-derived mesenchymal stem cells involves several stages. These pluripotent cells can differentiate into any cell type and release growth factors necessary for nerve regeneration and repair.

• Cellular response – Following nerve injury and initial degeneration, when the stem cells are administered, they activate the surrounding immune cells and supporting (Schwann) cells to release cytokines and growth factors to accelerate the healing response and promote nerve regeneration.
• Regrow Axons – Stem cells promote the growth of new axons at the end of damaged nerves, which play a crucial role in transmitting signals and regulating motor function.
• Remyelination – MSCs also support the regeneration of nerve cells in the protective covering or myelin sheath. This process is called remyelination and is necessary for restoring the nerves’ function in sending signals efficiently.
• Functional Recovery – As nerve regeneration and efficient signal transmission between nerve cells are established again, the functions of nerves in the affected areas improve, and patients experience a significant reduction in symptoms.

Role of Stem Cells In Repairing Nerve Damage

Stem cells repair damaged nerves caused by diabetic and peripheral neuropathy and aid in nerve regeneration. They stimulate the growth of new blood vessels through angiogenesis and enhance the restoration of the axons in the protective myelin sheath. These specialized cells possess anti-inflammatory and immunomodulatory properties, which reduce inflammation and regulate the immune system.

The therapeutic effects and diverse mechanisms of stem cells result in a smooth healing process of nerve injuries in the peripheral nervous system. Although stem cell therapy has the fantastic potential to regenerate damaged nerves and restore their function, success largely depends on the location of the nerve damage, the extent of the damage, the type of nerve injury, and the patient’s overall health.

Medical Studies On Effectiveness of Stem Cells In Treating Neuropathy

Recent studies on stem cell therapy for addressing diabetic and peripheral neuropathy show promising results in encouraging neuronal survival, reducing inflammation, and promoting axonal growth. MSCs are a powerhouse of cytokines, growth factors, and RNA, which support a healthy cellular environment and encourage nerve repair and regeneration by activating the healing response of the surrounding cells. Several studies and medical research indicate that stem cell-based treatments are effective in treating diabetic neuropathy and demyelinating polyneuropathy by eliminating their chronic inflammatory effects.

Reports on a small study of 10 female patients with diabetic neuropathy reveal that 50% of them experienced a significant reduction in pain and relief from other symptoms after six months. Moreover, their dependence on anti-neuropathic medicines was reduced, and there was a noticeable improvement in nerve function.

Success Rates of Stem Cell Treatment for Neuropathy

Multiple studies and clinical trials on stem cell therapy for neuropathy suggest that almost 80% of patients benefit from it, which has long-lasting results. The success rates of stem cell-based treatment depend on various factors, such as the type of neuropathy, the types of stem cells used, the number of stem cell doses, the severity of the condition, the patient’s age, and overall health.

Although several studies indicate positive clinical outcomes, more research is needed to determine a specific neuropathy type’s proper stem cell treatment approach to ensure its long-term efficacy and success rates.

Best Country for Stem Cell Therapy

Several countries worldwide offer high-quality stem cell treatments, such as Thailand, Germany, Singapore, South Korea, and Mexico. The cost of treatment in every country differs significantly because of the location, infrastructure, travel expenses, treatment facilities, and many other aspects.

Among all the countries mentioned above, Mexico is a leading destination for world-class stem cell therapy at affordable rates. The advanced healthcare infrastructure, cutting-edge technologies, and presence of qualified healthcare professionals make Mexico an ideal country for medical tourism.

While considering stem cell therapy in Mexico, Life Altering Stem Cell Therapy Institute is a top-rated clinic specializing in personalized cell therapies for more than twenty health conditions, from autoimmune conditions to age-related disorders, Alzheimer’s disease to Parkinson’s disease, and cardiovascular issues. Consult our healthcare professional for the best treatment advice based on your condition and medical history.

What is Male Infertility?

The World Health Organization (WHO) defines male infertility in humans as the inability to fertilize their female partners through unprotected and regular intercourse for 12 months or more. As per the latest statistics, over 30 million couples worldwide are facing infertility issues, with the highest numbers observed in African and Eastern European nations. Although infertility is associated with both men and women, almost 20% to 30% of couples experience difficulty in conceiving due to male infertility.

A decline in the sperm count over time, the diminished quality of the sperm, and abnormal blockages or functioning of the reproductive system result in infertility in men. Male infertility is one of the primary reasons for social distress among couples and their families, alongside mental and financial burdens. Hence, early diagnosis of the problem and proper medical intervention are necessary.

Types and Causes of Male Infertility

Male infertility can be of various types based on the causes and fertility parameters. Let’s understand each of the types and associated symptoms.

Erectile Dysfunction (ED) – It is a type of infertility disorder that occurs when a man is unable to maintain a firm erection that is long enough for sexual intercourse. Partners of patients with ED often face difficulty achieving pregnancy. Reduced sexual drive, difficulty getting an erection, difficulty keeping the erection, and unsatisfied sex are the common symptoms of erectile dysfunction.

Azoospermia – Azoospermia is a reproductive disorder in men characterized by the complete absence of sperm in the fluid after ejaculation. It happens because the testicles are unable to produce or release mature sperm. Prominent symptoms of Azoospermia are erectile dysfunction, swelling or lump around testicles, decreased hair on the body and face, and lower sexual desire.

Hypogonadism – Male hypogonadism is the body’s inability to produce enough testosterone, resulting in infertility and sexual problems. Testosterone is the hormone responsible for masculine growth and proper functioning of the reproductive organs in men. Reduced sex drive and erectile dysfunction are the effects of hypogonadism in males.

Other than biological reasons, various lifestyle and environmental factors also affect the fertility of a man, such as exposure to toxins, excessive smoking and alcohol drinking, obesity, anxiety issues, emotional stress, and depression. The next segment of this article sheds light on the potential of stem cells in treating male infertility and improving patient’s quality of life.

What are Spermatogonial Stem Cells?

Spermatogenesis is the process of developing male gametes or sperm cells by the testes. Spermatogonial stem cells (SSCs) are rare adult stem cells found in the male body that are crucial for maintaining the healthy spermatogenesis process. SSCs are considered the foundation of the male reproductive system and male fertility.

Spermatogonial stem cells are found in the basal membrane of seminiferous tubules and undergo cellular mitosis to promote differentiation, self-renewal, and formation of sperm cells. These cells play a critical role in maintaining a stable stem cell pool by developing mature spermatozoa over time.

Role of Mesenchymal Stem Cells In Promoting Spermatogonial Stem Cells

Mesenchymal stem cells (MSCs) are immature cells present in specific tissues in the human body and can differentiate and multiply into any cell type. They are also known as stromal cells, which help form organ or gland-specific cells or tissues by providing support and structure. They are found in the bone marrow, adipose or fat tissue, embryos, or umbilical cord tissue.

Several studies demonstrate that mesenchymal stem cells derived from human umbilical cord tissue have remarkable potential to grow into germ cells and address male infertility. Stem cell therapy using MSCs has been, therefore, a promising treatment to improve sperm count and sperm quality in patients suffering from infertility issues.

Spermatogenesis is a stem-cell-based mechanism where unspecialized stem cells differentiate into sperm cells to restore the functioning of male reproductive organs. Spermatogonial stem cells produced through cell differentiation of mesenchymal stem cells are used as a therapeutic alternative to treat impaired spermatogenesis and enhance fertility preservation.

How Does Spermatogonial Stem Cell Therapy Treat Male Infertility?

Cellular therapy using spermatogonial stem cells is a revolutionary treatment alternative for infertility issues in men, such as non-obstructive Azoospermia and impaired spermatogenesis. Stem cells regenerate healthy cells to replace the damaged spermatogenesis and restore fertility. SSCs are unique adult cells that can self-renew or regrow cells that will genetically contribute to future generations.

Recent studies have demonstrated that human SSCs have pluripotent properties and can differentiate into all cell lineages, including the three germ cell layers. Spermatogonial stem cell therapy helps in cell differentiation and growth of spermatozoa to help restore fertility. These cells contribute to creating a conducive microenvironment and growth factor stimulation.

Safety and Efficacy of the Stem Cell Therapy

Stem cell therapy for infertility treatment is typically safe and effective with no potential side effects. Also, numerous human studies and clinical trials indicate that results are satisfactory, with significant improvements in patients in terms of increased sex drive, better erection, and better sperm count and quality.

Though these findings demonstrate stem cell therapy as a safer alternative to traditional clinical treatments for male infertility, more research is needed to enhance its success rates and evaluate the potential risks.

Best Place to Get Stem Cell Therapy For Erectile Dysfunction

If you are seeking a reliable stem cell center in Mexico to treat male infertility due to erectile dysfunction, Life Altering Stem Cell Therapy Institute is a name you can always trust. We specialize in offering personalized stem cell therapy to every patient by addressing their unique problems and their underlying causes.

Our advanced stem cell therapy for erectile dysfunction has given hope to countless couples who are keen to start or expand their families. Connect with our medical team or visit our clinic in Mexico to start your journey towards enhanced fertility.

What are Diabetic Foot Ulcers?

A diabetic foot ulcer (DFU) is a wound or sore on the bottom of the feet that is very common in diabetes patients. It is a severe complication or side effect of diabetes mellitus associated with infection, amputation, and, in worst cases, death. Patients with uncontrolled blood sugar for a long time develop ulcers on the bottom of the feet, particularly in areas that experience pressure and repetitive trauma.

As mentioned earlier, 15% of diabetes patients report foot ulcers, out of which 6% are hospitalized due to extreme levels of infection or ulcer-related complications. DFU can develop in diabetes patients of both Type 1 and Type 2 and requires immediate medical intervention to prevent the worst possible outcomes, like amputation.

Causes of Diabetic Foot Ulcers

Poor blood circulation is identified as one of the most common causes of diabetic foot ulcers due to lack of flow of blood to the feet. Damage to the nerves, wounds, excessive pressure, or trauma on the foot are also factors responsible for DFU in patients with high blood glucose levels (hyperglycemia).

Lack of proper blood circulation also slows down the healing process of foot ulcers, resulting in further health deterioration. Hence, managing blood sugar levels is essential to prevent the growth of foot ulcers and fight infections from ulcers. Also, maintaining proper foot hygiene with regular cleaning and moisturizing and using clean shoes and socks is necessary for patients with foot ulcers.

Symptoms of Diabetic Foot Ulcers

Diabetic foot ulcer is a challenging condition that impacts the lives of many diabetic patients. The common symptoms include:

• Drainage from the infected wound or ulcers
• Unusual swelling, redness, or irritation
• Black or dead tissue (Escher) surrounding the foot ulcer
• Painful tingling or numbness in the area or the entire bottom of the foot
• Loss of sensation or feeling

Healing Mechanism of Stem Cells for Diabetic Foot Ulcers

Stem cells are undifferentiated immature cells that have the power to develop and multiply into healthy cells to replace damaged cells and treat various types of medical conditions. The latest research shows that mesenchymal stem cells isolated from human umbilical cord tissue have immense potential to repair and regenerate skin cells, which can effectively improve symptoms of foot ulcers and prolong the lives of affected individuals.

While steroids and other traditional treatments aim to temporarily relieve symptoms, stem cells address their root cause and deliver long-term positive clinical outcomes. The therapeutic effects of stem cell treatment for diabetic foot ulcers are diverse, ranging from exerting anti-inflammatory effects to regulating the immune system at the site of injury, promoting tissue regeneration, and accelerating the healing response.

Furthermore, umbilical cord tissue-derived mesenchymal stem cells are known for their pluripotent characteristic, which allows them to form any cell type, including nerve and skin cells. Their capability to quickly regrow skin cells at the foot ulcer site promotes rapid wound closure or healing, reducing the risk of infection.

Improvements Seen in Patients After Stem Cell Therapy

Stem cell treatment for diabetic foot ulcers has proven to be quite effective. It promises to enhance vascular function and improve healing rates of foot ulcers in patients with peripheral and diabetic neuropathy. Administration of stem cells is generally considered safe, with no adverse reactions impacting patients’ quality of life.

The significant improvements observed in patients with DFU after the therapy are:

• No more drainage from the infected wound or ulcer
• Decrease in pain and soreness
• Reduction in the size of the ulcer
• Reduced blisters or wounds
• Controlled blood sugar level
• Reduced numbness or tingling sensation
• Pain-free walking

Early medical interventions in diabetic foot ulcers with stem cell therapy can result in the above substantial improvements in healing. It helps ease pain and reduces the wound’s size by promoting healthy tissue growth.

Success Rates of Stem Cell Treatment For Diabetic Foot

Stem cell treatment has shown promising results improving the patient’s conditions, with success rates of around 80%. The factors that influence the efficacy or success rates of stem cell treatment in DFU are:

• Rate of angiogenesis – growth or formation of new blood vessels
• Pain scores – the intensity of pain in the foot, particularly in the affected wound
• Complete healing time – how fast the ulcer heals through healthy tissue regeneration
• Ulcer size reduction – the quicker the size reduces, the better
• Amputation rate – decrease in chances of foot amputation

Overall, stem cell therapy has shown positive outcomes in halting the progression of foot ulcers with regeneration of skin tissue and better wound healing.

Why Choose Stem Cell Therapy For Diabetic Foot Ulcers

Stem cell therapy offers advantages over medications and other traditional treatments to heal foot ulcers.

• The process is less or minimally invasive and primarily performed in an outpatient department under the clinical supervision of healthcare professionals.
• The therapy is safe, with zero or no significant side effects.
• There is no risk of immune or allergic reactions as the chances of cell rejection in umbilical cord tissue-derived mesenchymal stem cells are zero.
• There are no adverse complications or transmissible diseases.
• The therapy requires a minimum hospital stay.
• The recovery period is short, and the therapy delivers long-lasting results.

What is Prostate Cancer?

The prostate is a walnut-sized gland located below the bladder in men and produces fluid for semen. When cells in the gland start growing abnormally, they form tumors and lead to prostate cancer. Although, in most cases, cancer tends to grow and spread slowly in the gland, it can spread very quickly in rare cases. Prostate cancer mainly affects older men and results in poor quality of life. 

Numerous research suggests that prostate cancer may originate from pre-cancerous conditions in certain instances. These conditions are occasionally detected during a prostate biopsy, a procedure involving the extraction of small tissue samples from the prostate to examine for signs of cancer. 

The Science Behind Using Stem Cells As A Target For Prostate Cancer Therapy

Traditional treatments for Prostate cancer include the removal of the glands surgically to get rid of the tumor. Sometimes, doctors conduct radiation therapy to ensure that the cancer cells do not spread to other organs. A doctor may also suggest immunotherapy, hormone therapy, and chemotherapy depending on the stage of the cancer and how fast the cancer cells are growing in the gland. While these treatments are proven effective, there are some limitations and possible risks of side effects that necessitate safe and alternative therapy.  

Stem cells are unspecialized cells capable of differentiating and developing into cell types to help in tissue repair and regeneration, accelerating the body’s healing response. Stem cells hold great potential to replace cancer cells with healthy ones and stop cancer progression in the gland. 

Furthermore, stem cells actively interact with the immune system and regulate its response with their distinctive immunomodulatory properties. In prostate cancer therapy, stem cells target the cancer cells directly and strengthen the body’s natural defense against malignant tumors. This dual-action mechanism of stem cells has proved revolutionary in comprehensive cancer treatments, including prostate cancer. 

Importance of Personalized Treatment Approaches with Stem Cells

Most stem cell therapy institutes plan and prepare personalized therapy for every cancer patient based on the unique body needs and severity of the condition. Tailoring a bespoke treatment strategy for cell therapy optimizes the efficiency of the treatment and increases the chances of success. A personalized stem cell treatment effectively addresses a patient’s unique characteristics and vulnerabilities. It can help slow the progression and improve patient outcomes and quality of life. 

Tailored treatment approaches using stem cells indicate a pathbreaking advancement in prostate cancer therapy. They offer a more precise and effective intervention in helping identify and eliminate cancer cells. Further, personalized and targeted cell therapy minimizes the chances of damage to the surrounding environment comprising healthy cells and maximizes its impact on the cancer cells. 

Conclusion

Stem cell therapy has shown favorable clinical outcomes in treating prostate cancer. Medical researchers continually explore new approaches to improve its efficacy and success rates. The stem cell field is rapidly evolving and brings hope to patients of prostate cancer in finding the best possible cure for this debilitating disease. Consulting a healthcare professional at a stem cell therapy clinic specializing in cancer care is necessary for personalized guidance and treatment based on your body’s needs. 

Life Altering Stem Cell Therapy Institute is Mexico’s best stem cell center, known for its cutting-edge cellular treatments for more than twenty medical conditions. Book a consultation today to learn more about stem cell therapy and take the first step toward holistic healing.

What is Paralysis?

Paralysis is a condition that occurs due to a permanent or temporary loss of motor function in one or more muscles. Inadequate or non-functioning of the nervous system makes an individual incapable of moving or controlling specific body parts, including the head, arms, hands, legs, feet, and more. Paralysis is a multi-faceted challenge that impacts physical mobility and mental well-being.

How Stem Cells Can Help in Recovery From Paralysis

New advancements in medical science, mainly stem cell therapy for Paralysis, have made patients quite hopeful. Stem cells are undifferentiated and immature cells that can differentiate and form any cell type to repair, replace, and regenerate tissues. Their distinct cell differentiation and high proliferation capacity to regenerate nerve cells make them ideal for treating Paralysis and restoring nerve function and mobility.

Paralysis can be of different types based on their causes, such as spinal cord injury, cerebral palsy, and stroke-induced Paralysis. Stem cells help recover from these conditions by regenerating new nerve pathways and repairing damaged tissues. They restore motor skills and brain function through healthy cell regeneration to treat Paralysis due to stroke. In the case of cerebral palsy treatment, stem cells reduce spasticity and improve motor function.

Types of Stem Cells Used in Paralysis Treatment

Various types of stem cells are used in the paralysis treatment, which are as follows:

• Neural stem cells repair and replace the damaged neurons and improve the functioning of the nervous system.
• Mesenchymal stem cells are extracted from the bone marrow, adipose tissue, or fat. They are multipotent and capable of differentiating into multiple cell types.
• Umbilical cord-tissue-derived mesenchymal stem cells are pluripotent cells with high anti-inflammatory and immunomodulatory properties.
• Induced pluripotent stem cells are reprogrammed to exhibit properties of pluripotent mesenchymal stem cells, which can develop in any cell type.

Benefits of Stem Cell Therapy in Paralysis Treatment

Stem cell treatment is effective in treating Paralysis and has helped restore the normal functioning of the nervous system. Stem cells use the body’s natural healing abilities to regenerate healthy neurons, replace dead nerve cells, reduce inflammation, and prevent further damage to the neurons.

The key benefits that stem cell therapy for Paralysis offer to patients are:

• Stem cells may secrete growth factors that help regenerate axons.
• Stem cells replace lost neural cells, which could lead to remyelination, new circuits, or scaffolding and nutrition.
• Stem cells may be transplanted to bridge axons in damaged regions, which may help nerve fibers regrow.
• Stem cells are induced to form precursors that remyelinate damaged axons.
• Stem cells remove or inactivate growth inhibitory factors.
• Stem cells promote neovascularization, which may support axon regrowth.
• It improves the microenvironment at the injury site.
• Stem cell therapy enhances nutritional support.
• The cells have immunomodulatory properties that modulate inflammation.

Potential Risks Associated With the Treatment

Although stem cell therapy is considered entirely safe and has no significant side effects, there are some possible risks that every patient must know before making a final decision.

• Mild swelling, pain, or redness at the site of injection
• Risks of infections, rash, and allergies
• Chances of cell rejection by the immune system
• Unpredictability regarding the efficacy and outcomes

Results To Expect After Stem Cell Therapy

Patients can expect changes in their physical condition slowly after a few weeks or months as the nervous system responds to the treatment.

• Improvement in muscle strength and ability to make movements easily
• There is enhanced coordination and improved control over physical movements
• Restoration in sensation as it improves the overall sensory experiences

Regular check-ups with the healthcare service provider are necessary to monitor progress and improvements in the symptoms. Rehabilitation and supportive physical therapy accelerate the healing process and optimize the recovery process.

Success Rates of Stem Cell Treatment for Paralysis

Results of several clinical trials and studies demonstrate that the success rates of stem cell treatment are near about 60 to 70%. However, patients must understand that the efficacy of the treatment depends on the type of Paralysis, the patient’s age, stem cell doses, and current condition or its severity.

What is Stem Cell Therapy?

Stem cell therapy is a regenerative medicine that uses stem cells to repair and regenerate damaged cells or tissues. It is a promising approach that utilizes stem cells’ unique properties to treat various diseases, including Type 2 diabetes, autoimmune conditions, neurodegenerative diseases, and more. Research and clinical studies indicate that this novel therapeutic approach helps manage blood glucose levels in Type 2 diabetes patients by regrowing insulin-producing cells and restoring beta cell function.

Types of Stem Cells Used in Type 2 Diabetes Treatment

Multipotent or pluripotent mesenchymal stem cells (MSCs) are used for treating Type 2 Diabetes. They can be derived from various sources, either the patient’s body or donors. The primary sources of stem cell collection are embryos, bone marrow, adipose tissue (fatty tissue), and umbilical cord tissues.

• Embryonic stem cells are derived from early-stage embryos and can develop into any cell type within the body. They hold significant potential for diabetes treatment.
• Adult stem cells are present in diverse tissues in the body, such as the bone marrow, adipose tissue (fatty tissue), and umbilical cord. They exhibit a more multipotent differentiation capacity compared to embryonic stem cells. Nevertheless, they still hold the potential to generate insulin-producing beta cells.
• Induced pluripotent stem (iPS) cells, originating from adult skin or blood cells that have undergone genetic reprogramming to exhibit properties of embryonic stem cells, present a viable alternative.

Most medical scientists prefer using human umbilical cord tissue because it contains abundant mesenchymal stem cells with high proliferation capacity. These cells are more robust than other sources and can differentiate into any cell type faster.

How Does Stem Cell Therapy Work For Type 2 Diabetes Work?

Multipotent or pluripotent stem cells can differentiate into insulin-producing beta cells to replace damaged cells and maintain the insulin level. The administered stem cells result in the development of new blood vessels that accelerate the secretion of growth factors to regulate the immune system. The stem cells create a supportive microenvironment to expedite the process of stem cell differentiation and healing response.

Utilizing stem cells helps regenerate pancreatic or insulin-producing beta cells, which boosts the body’s insulin level. Mesenchymal stem cell therapy suppresses the immune system, reduces inflammation, and repairs damaged pancreatic tissues.

Stem cell treatments help in managing Type 2 diabetes in the following ways.

• Immune Modulation – Stem cells possess immunomodulatory properties that regulate the immune system response in the pancreas, restoring its function in releasing insulin hormone to control blood glucose levels.
• Vascular Repair – Stem cells effectively address vascular complications in diabetes patients. They repair or replace damaged tissues and promote the growth of new blood vessels, improving circulation and tissue healing.
• Anti-inflammatory effects – Stem cells’ anti-inflammatory properties help reduce inflammation and enhance insulin resistance, improving the overall health of diabetic patients.
• Beta Cell Regeneration – Type 2 diabetes destroys the insulin-producing beta cells and affects beta function, leading to uncontrolled sugar levels in the blood. Stem cells have remarkable potential to regrow beta or pancreatic cells to replace diseased ones.

Preliminary Procedures and Stem Cell Therapy Process

Before stem cell treatment for Type 2 diabetes, physicians examine the patient’s blood sugar level and other blood counts and assess the overall health condition to determine the feasibility of conducting therapy with mesenchymal stem cells. The patient’s medical history, allergies, pre-existing diseases, and health and lifestyle habits are also considered to qualify the patient for the therapy.

The prepared stem cells are injected intravenously via an IV dip, which takes one to two hours to complete. This is a standardized procedure for stem cell administration, and doctors monitor it to ensure the patient’s safety and comfort.

Healthcare providers conduct regular follow-ups to track the patient’s progress and improvement in the condition. Blood tests might be performed frequently to check the sugar level and assess how the body responds to the newly introduced stem cells.

Read Also: Stem Cell Treatment: Recent Advancements And New Applications

How Stem Cell Treatment Benefits Type 2 Diabetes Patients

Stem cell treatment for Type 2 diabetes is a safe and effective option for managing symptoms and improving the patient’s condition. After a few weeks of receiving stem cells, patients have experienced overall health improvement in the following ways.

• Blood sugar or glucose level stabilizes
• The wounds and ulcers caused by diabetes start healing
• Elimination of symptoms, such as frequent urination, hunger, and thirst
• Increased level of energy and stamina
• Reduced dependence on high doses of diabetic-controlling medicines

What is Avascular Necrosis (AVN)?

Avascular Necrosis or Osteonecrosis is a condition that causes bone tissues to die due to a lack of blood flow. It usually results from trauma or excessive fat deposits in weight-bearing joints, such as hips and knees. If left untreated, the consequences can be severe, leading to fractures, joint collapse, persistent pain, and limited mobility.

Osteonecrosis progresses when the bone cells in the joints (osteoblasts) cannot repair themselves due to decreased blood flow to the bones, start deteriorating, and eventually die.

Symptoms of Avascular Necrosis of the Hip

The early stages of Avascular Necrosis are mostly symptom-free, but with time, the affected joints in the hip start hurting when excessive pressure or weight is applied. Due to AVN, the skeletal structure in the portion below the hips, i.e., the upper leg, weakens, and the ball portion of the hip and joint socket collapses.

Other common symptoms of AVN noticeable in patients in later stages are:

• Persistent pain in the hips, buttocks, thighs, and knees
• Stiffness in the joints
• Limited mobility or range of motion
• Difficulty walking, bending, climbing, or standing

Read Also: Can Stem Cell Therapy Provide Relief From Chronic Knee Pain?

Traditional Treatment Approaches for Avascular Necrosis of the Hip

Although no medical treatment has proven effective for arresting or preventing AVN, conservative and non-surgical options may improve the symptoms and provide relief. However, medical management and treatments depend on the location of the AVN, the condition severity, the patient’s age, and overall health.

Non-surgical treatments include physiotherapy, pain-relief medicines, crutches, walkers, rest, reduced weight bearing, and electrical stimulation. Surgical procedures are the only option when these options fail to provide relief. Surgical treatments include total hip replacement, core decompression, bone graft, and total hip arthroplasty.

How Stem Cell Therapy Can Relieve Pain from Avascular Necrosis?

In exploring alternative treatment avenues to AVN, stem cell therapy is getting much attention because of its high differentiation and regenerative potential. Moreover, it prevents the need for complicated, painful, and invasive hip replacement surgery, which has a lengthy recovery period.

In the last few years, medical science has experienced a considerable shift in Avascular Necrosis treatment as stem cell therapy emerged as a promising treatment approach. Mesenchymal stem cells can reverse the damage by replacing bone cells in the affected hip joints with healthy cells and reducing pain and inflammation.

The five most important factors that make stem cell therapy stand out as a suitable treatment option for many are:

• Tissue regeneration – When stem cells are injected into the affected joints, they differentiate into osteoblasts (bone cells) and promote tissue regeneration. They replace the dead cells and repair the damaged ones, promoting functional recovery of the hip joints.
• Targeted Precision – Stem cell therapy for hip pain due to AVN provides a targeted precision approach to cell delivery. Doctors inject healthy and concentrated stem cells into the injured site to accelerate the regenerative and reparative process. The strategy focuses directly on the damaged or dead bone tissues and eliminates chances of collateral damage to the surrounding environment.
• Lower Risks – Surgical interventions for AVN, such as hip replacement, are inherently complicated and carry many risks. However, stem cell therapy is minimally invasive. Stem cells are harvested from the patient’s body or umbilical cord tissue-derived mesenchymal stem cells, reducing the chances of cell rejection or post-therapy complications.
• Holistic Healing – In addition to effectively addressing pain and other debilitating symptoms of AVN, stem cell treatments stimulate the body’s innate regenerative potential and promote holistic healing. The newly introduced stem cells target the root cause of the AVN, supporting sustainable relief and recovery.
• Quick recovery – The recovery period for stem cell therapy is significantly shorter than that for surgical interventions, and patients can usually leave the hospital on the same day and return to work within two to three days with a restricted range of motion in the affected joints.

Stem cell therapy offers a lasting and comprehensive treatment solution compared to surgical or traditional alternatives. Also, the targeted stem cell administration maximizes the effectiveness of the treatment.

Read Also: Healing Power Of Stem Cell Therapy: A Comprehensive Guide

Final Thoughts

Stem cell therapy has emerged as a pathbreaking solution for treating Avascular Necrosis. This noninvasive treatment intervention has given millions hope to combat this progressive condition and lead healthier lives. Cellular healing in AVN ensures patients regain their ability to walk, stand, and lean without any difficulty or discomfort. There is a significant reduction in pain, swelling, and stiffness in the affected joints.

The remarkable potential of stem cell treatments in the regeneration of bone cells in the avascular area of the hip bone improves function, reducing the need for hip replacement surgery.

About Life Altering Stem Cell Therapy Institute

Life Altering Stem Cell Therapy Institute (LASCTI) stands out as Mexico’s best stem cell center for many health ailments, from autoimmune diseases to heart problems, aging, and orthopedic conditions. We boast a team of highly qualified and internationally recognized stem cell specialists and physicians. They ensure the highest standard of treatment and care with their extensive years of clinical experience in stem cell therapy and advanced research.

LASCTI has a proven track record of clinical success in stem cell therapy, with high positive outcomes and patient satisfaction. Our expertise, cutting-edge techniques, and holistic care make us a top choice for international patients for stem cell therapy in Mexico. Contact our medical team to discuss your health concerns, and we will solve your problem.